Figure S5. Celsr1 is localized to the periphery of cells during tracheoesophageal separation, related to Figure 6. [continued panels e-M] S5E-H: Time course of Celsr1 immunostaining during Xenopus trachea-esophageal morphogenesis. Diagrams depict Celsr1/Rab11a localization during foregut separation. S5I-M: Celsr1:Rab11a colocalization is significantly decreased in rab5a Xenopus mutants, but Celsr1 cellular localization is not significantly altered in dnm2, rab5a, and rab11a Xenopus mutants (mean min/max, 1W-ANOVA, **p<0.01. n=3-5 cells, 5 embryos analyzed).
Image published in: Edwards NA et al. (2025)
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| Gene | Synonyms | Species | Stage(s) | Tissue |
|---|---|---|---|---|
| celsr1 | cdhf9, flamingo 2, fmi2, hfmi2, me2 | X. tropicalis | Sometime during NF stage 37 and 38 to NF stage 41 | trachea esophagus tracheoesophageal septum |
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