Summary Literature (0)

DOID:5688 - Werner syndrome

Disease Ontology Definition:An autosomal recessive disease characterized by premature aging and age-related phenotypes such as atherosclerosis, arteriosclerosis, cataracts, osteoporosis, soft tissue calcification, premature thinning, graying, and loss of hair, as well as a high incidence of some types of cancers. In 90% of the cases it is that has material basis in mutations in the WRN gene, on chromosome 8.

Synonyms: WS, Werner's syndrome, adult premature ageing syndrome, adult progeria,

Echinobase Genes : wrn


OMIM:

MIM:277700 - werner syndrome; wrn

Other Model Organisms: AGR, MGI, ZFIN, FlyBase, WormBase, RGD

Ontology Viewers: Disease Ontology, EMBL-EBI, OLSVis tree view, Ontobee