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ECB-GENEPAGE-23181751
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???displayGene.symbol??? rag1
 :Symbol Status
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Curated
???displayGene.name??? recombination activating 1
: Name Status
:
Curated
???displayGene.synonyms???
LOC110976285
,
Rag1L
,
recombination activating gene 1-like
,
Sp-Rag1l
,
SPU_027600
[-]
(
???displayGene.geneFunction??? Catalytic component of the RAG complex, a multiprotein complex that mediates the DNA cleavage phase during V(D)J recombination. V(D)J recombination assembles a diverse repertoire of immunoglobulin and T-cell receptor genes in developing B and T-lymphocytes through rearrangement of different V (variable), in some cases D (diversity), and J (joining) gene segments. In the RAG complex, RAG1 mediates the DNA-binding to the conserved recombination signal sequences (RSS) and catalyzes the DNA cleavage activities Protein Function
:???displayGene.geneInteractants???
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Diseases: Disease Ontology: Omenn syndrome
MIM:
OMENN SYNDROME
External Links:
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