Click here to close Hello! We notice that you are using Internet Explorer, which is not supported by Echinobase and may cause the site to display incorrectly. We suggest using a current version of Chrome, FireFox, or Safari.
Development 2011 Sep 01;13817:3613-23. doi: 10.1242/dev.058172.
Show Gene links Show Anatomy links

The evolution of nervous system patterning: insights from sea urchin development.

Angerer LM , Yaguchi S , Angerer RC , Burke RD .

Recent studies of the sea urchin embryo have elucidated the mechanisms that localize and pattern its nervous system. These studies have revealed the presence of two overlapping regions of neurogenic potential at the beginning of embryogenesis, each of which becomes progressively restricted by separate, yet linked, signals, including Wnt and subsequently Nodal and BMP. These signals act to specify and localize the embryonic neural fields - the anterior neuroectoderm and the more posterior ciliary band neuroectoderm - during development. Here, we review these conserved nervous system patterning signals and consider how the relationships between them might have changed during deuterostome evolution.

PubMed ID: 21828090
PMC ID: PMC3152920
Article link: Development
Grant support: [+]

Genes referenced: LOC100887844 LOC590297 nodall

References [+] :
Angerer, A BMP pathway regulates cell fate allocation along the sea urchin animal-vegetal embryonic axis. 2000, Pubmed, Echinobase