ECB-IMG-208593
Echinobase Image ID: 208593
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Figure 6. PLIN2-dependent lipid droplet organization mitigates Vibrio splendidus-induced ER stress. Coelomocytes were transfected with siNC or siplin2 for 24 h, followed by infection with V. splendidus (MOI = 10) for 12 h in the absence or presence of 500 μM OA. Relative mRNA expression of bip, ire1α, perk, atf6, xbp1, and chop was detected by qRT-PCR. Data are presented as the mean ± SD from three independent biological replicates. Significantly different experimental groups: * p < 0.05, ** p < 0.01 by one-way ANOVA. atf6, cyclic AMP-dependent transcription factor atf-6 alpha; bip, endoplasmic reticulum chaperone bip; chop, DNA damage-inducible transcript 3 protein; ire1α, serine/threonine-protein kinase/endoribonuclease ire1α; OA, oleic acid; perk, eukaryotic translation initiation factor 2-alpha kinase 3; plin2, perilipin 2; xbp1, x-box-binding protein 1. Image published in: Fan H et al. (2026) Image downloaded from an Open Access article in PubMed Central. © 2026 by the authors. Larger Image Printer Friendly View |