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Figure 3. Expression pattern of transcription factors Hey1 and Irf1 in the developing endoderm. a: Transverse section through anterior endoderm at NF32 showing expression of hey1 restricted to the outer periphery of the endoderm. b: Expression of hey1 is more diffuse within the endoderm of the NF36 embryo, transverse section. c: NF44 whole gut showing expression of hey1 throughout the stomach, liver and pancreas. d: Transverse section through anterior endoderm at NF32 showing expression of irf1 throughout the entire endoderm. e: Transverse section at NF36 shows restricted expression of irf1 along the dorsolateral endoderm. f: NF44 whole gut showing expression of irf1 throughout the stomach, liver, pancreas and in the intestine. dle, dorsolateral endoderm; ve, ventral endoderm; e, endoderm; l, liver; st, stomach; p, pancreas. Reproduced with permission of the Publisher, John Wiley & Sons.

Image published in: Bilogan CK and Horb ME (2012)

Copyright © 2012. Image reproduced with permission of the Publisher, John Wiley & Sons.

GeneSynonymsSpeciesStage(s)Tissue
hey1.Lbc8, chf2, herp2, hesr1, hrt-1, hrt1, oaf1, XHRT1X. laevisThroughout NF stage 32dorsal endoderm
endoderm
irf1.LX. laevisSometime during NF stage 32 to NF stage 35 and 36dorsal endoderm
endoderm
hey1.Lbc8, chf2, herp2, hesr1, hrt-1, hrt1, oaf1, XHRT1X. laevisThroughout NF stage 44pancreas
stomach
liver
alimentary system
irf1.LX. laevisThroughout NF stage 44pancreas
stomach
liver
alimentary system
intestine

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