Figure 7. XSNT-AS disrupts neural and mesoderm-derived tissues. In situ hybridization of Nrp-1 (pan-neural) transcripts in an uninjected embryo (un; A) and in a XSNT1-AS (80 ng) -injected embryo (AS; B). Immunostaining of muscle (12/101 antibody) in an uninjected embryo (un; C) and an XSNT-AS (80 ng) -injected embryo (AS: D). Immunostaining of notochord (Tor-70 antibody) in an uninjected embryo (un; E) and XSNT-AS (80 ng) -injected embryos (AS; F-H). N, neural tissue; Mu, muscle; Nt, notochord.
Image published in: Akagi K et al. (2002)
Copyright © 2002. Image reproduced with permission of the Publisher, John Wiley & Sons.
| Gene | Synonyms | Species | Stage(s) | Tissue |
|---|---|---|---|---|
| nrp1.L | A5 antigen, LOC108718763, neuropilin, neuropilin-1, np-1, npn-1, nrp, nrp-1, pNPG152 | X. laevis | Throughout NF stage 29 and 30 | brain forebrain midbrain hindbrain otic vesicle neuroectoderm anterior neural tube eye |
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