Fig. 1. Identification of three spry genes in a stage 51 limb bud transcriptome. (A) stacked column graph showing percentage of reads originating from each third of the limb bud: proximal, middle or distal. fgf8 and -8b are included for comparison. (B) Bar graph to show relative numbers of reads for each transcript across the whole limb, normalised for transcript size. Higher numbers of reads indicate higher levels of expression. (CâF) In situ hybridisation to stage 32 X. laevis embryos for spry1a, 2, 3 and 4. Abbreviations: ba: branchial arches, mhb: mid/hindbrain boundary, op: olfactory placode, ov: otic vesicle, sc: spinal cord, tb: tail bud.
Image published in: Wang YH and Beck CW (2014)
Copyright © 2014. Image reproduced with permission of the Publisher, Elsevier B. V.
| Gene | Synonyms | Species | Stage(s) | Tissue |
|---|---|---|---|---|
| spry1.L | sprouty, sprouty 1, sprouty-1, sprouty1, spry1-a, spry1-b, xspry1, Xtsprouty1 | X. laevis | Throughout NF stage 32 | olfactory placode midbrain-hindbrain boundary otic vesicle tail bud pharyngeal arch mandibular arch branchial arch |
| spry2.S | sprouty 2, sprouty-2, sprouty2, Xsprouty2, xspry2, Xtsprouty2 | X. laevis | Throughout NF stage 32 | olfactory placode midbrain-hindbrain boundary otic vesicle pharyngeal arch mandibular arch branchial arch |
| spry3.S | sprouty 3, sprouty-3, sprouty3 | X. laevis | Throughout NF stage 32 | otic vesicle spinal cord trigeminal ganglion |
| spry4.L | sprouty 4, sprouty-4, sprouty4 | X. laevis | Throughout NF stage 32 | olfactory placode otic vesicle tail bud pharyngeal arch mandibular arch branchial arch |
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