Click
here to close Hello! We notice that
you are using Internet Explorer, which is not supported by Echinobase
and may cause the site to display incorrectly. We suggest using a
current version of Chrome,
FireFox,
or Safari.
Evol Appl
2016 Oct 01;99:1124-1132. doi: 10.1111/eva.12404.
Show Gene links
Show Anatomy links
Loss of genetic diversity as a consequence of selection in response to high pCO2.
Lloyd MM
,
Makukhov AD
,
Pespeni MH
.
???displayArticle.abstract???
Standing genetic variation may allow for rapid evolutionary response to the geologically unprecedented changes in global conditions. However, there is little known about the consequences of such rapid evolutionary change. Here, we measure genetic responses to experimental low and high pCO 2 levels in purple sea urchin larvae, Strongylocentrotus purpuratus. We found greater loss of nucleotide diversity in high pCO 2 levels (18.61%; 900 μatm) compared to low pCO 2 levels (10.12%; 400 μatm). In the wild, this loss could limit the evolutionary capacity of future generations. In contrast, we found minimal evidence that purple sea urchin larvae physiologically respond to high pCO 2 through alternative splicing of transcripts (11 genes), despite a strong signal of alternative splicing between different developmental stages (1193 genes). However, in response to high pCO 2, four of the 11 alternatively spliced transcripts encoded ribosomal proteins, suggesting the regulation of translation as a potential response mechanism. The results of this study indicate that while the purple urchin presently may have enough standing genetic variation in response to rapid environmental change, this reservoir of resilience is a finite resource and could quickly diminish.
Figure 1. Permutation density plots of an anova to test the significance of (A) day, (B) pCO
2 level, and (C) the interaction between day × pCO
2 level on nucleotide diversity as measured by π. Horizontal lines mark the observed P‐value for each factor.
Anders,
Detecting differential usage of exons from RNA-seq data.
2012, Pubmed
Anders,
Detecting differential usage of exons from RNA-seq data.
2012,
Pubmed
Barrett,
Adaptation from standing genetic variation.
2008,
Pubmed
Byrne,
The stunting effect of a high CO2 ocean on calcification and development in sea urchin larvae, a synthesis from the tropics to the poles.
2013,
Pubmed
,
Echinobase
Cameron,
SpBase: the sea urchin genome database and web site.
2009,
Pubmed
,
Echinobase
Danecek,
The variant call format and VCFtools.
2011,
Pubmed
Degner,
Effect of read-mapping biases on detecting allele-specific expression from RNA-sequencing data.
2009,
Pubmed
Dixon,
CORAL REEFS. Genomic determinants of coral heat tolerance across latitudes.
2015,
Pubmed
Doney,
Ocean acidification: the other CO2 problem.
2009,
Pubmed
,
Echinobase
Dorey,
Assessing physiological tipping point of sea urchin larvae exposed to a broad range of pH.
2013,
Pubmed
,
Echinobase
Dupont,
Impact of near-future ocean acidification on echinoderms.
2010,
Pubmed
,
Echinobase
Feely,
Evidence for upwelling of corrosive "acidified" water onto the continental shelf.
2008,
Pubmed
Gaylord,
Functional impacts of ocean acidification in an ecologically critical foundation species.
2011,
Pubmed
Guinotte,
Ocean acidification and its potential effects on marine ecosystems.
2008,
Pubmed
Hamdoun,
Embryo stability and vulnerability in an always changing world.
2007,
Pubmed
Hoffmann,
Climate change and evolutionary adaptation.
2011,
Pubmed
Hofmann,
High-frequency dynamics of ocean pH: a multi-ecosystem comparison.
2011,
Pubmed
Hughes,
Genetic diversity enhances the resistance of a seagrass ecosystem to disturbance.
2004,
Pubmed
Hönisch,
The geological record of ocean acidification.
2012,
Pubmed
Irimia,
Quantitative regulation of alternative splicing in evolution and development.
2009,
Pubmed
Jump,
Environmental change and the option value of genetic diversity.
2009,
Pubmed
Jump,
Running to stand still: adaptation and the response of plants to rapid climate change.
2005,
Pubmed
Kim,
TopHat2: accurate alignment of transcriptomes in the presence of insertions, deletions and gene fusions.
2013,
Pubmed
Kroeker,
Meta-analysis reveals negative yet variable effects of ocean acidification on marine organisms.
2010,
Pubmed
Lande,
THE ROLE OF GENETIC VARIATION IN ADAPTATION AND POPULATION PERSISTENCE IN A CHANGING ENVIRONMENT.
1996,
Pubmed
Marden,
Quantitative and evolutionary biology of alternative splicing: how changing the mix of alternative transcripts affects phenotypic plasticity and reaction norms.
2008,
Pubmed
Menge,
Top-down and bottom-up community regulation in marine rocky intertidal habitats.
2000,
Pubmed
Pan,
Experimental ocean acidification alters the allocation of metabolic energy.
2015,
Pubmed
,
Echinobase
Pespeni,
Evolutionary change during experimental ocean acidification.
2013,
Pubmed
,
Echinobase
Pespeni,
Signs of adaptation to local pH conditions across an environmental mosaic in the California Current Ecosystem.
2013,
Pubmed
,
Echinobase
Pespeni,
Signals of selection in outlier loci in a widely dispersing species across an environmental mosaic.
2013,
Pubmed
,
Echinobase
Pörtner,
Ecology. Physiology and climate change.
2008,
Pubmed
Reusch,
Ecosystem recovery after climatic extremes enhanced by genotypic diversity.
2005,
Pubmed
Sodergren,
The genome of the sea urchin Strongylocentrotus purpuratus.
2006,
Pubmed
,
Echinobase
Somero,
The physiology of climate change: how potentials for acclimatization and genetic adaptation will determine 'winners' and 'losers'.
2010,
Pubmed
Somero,
The physiology of global change: linking patterns to mechanisms.
2012,
Pubmed
Stumpp,
CO2 induced seawater acidification impacts sea urchin larval development I: elevated metabolic rates decrease scope for growth and induce developmental delay.
2011,
Pubmed
,
Echinobase
Sunday,
Evolution in an acidifying ocean.
2014,
Pubmed
Trapnell,
TopHat: discovering splice junctions with RNA-Seq.
2009,
Pubmed
Tu,
Gene structure in the sea urchin Strongylocentrotus purpuratus based on transcriptome analysis.
2012,
Pubmed
,
Echinobase
Tu,
Quantitative developmental transcriptomes of the sea urchin Strongylocentrotus purpuratus.
2014,
Pubmed
,
Echinobase
Xue,
Specialized ribosomes: a new frontier in gene regulation and organismal biology.
2012,
Pubmed
Zhang,
Control of hematopoietic stem cell emergence by antagonistic functions of ribosomal protein paralogs.
2013,
Pubmed
van de Geijn,
WASP: allele-specific software for robust molecular quantitative trait locus discovery.
2015,
Pubmed