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Dev Biol 2014 Jan 15;3852:160-7. doi: 10.1016/j.ydbio.2013.11.019.
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Quantitative developmental transcriptomes of the sea urchin Strongylocentrotus purpuratus.

Tu Q , Cameron RA , Davidson EH .

Development depends on the precise control of gene expression in time and space. A critical step towards understanding the global gene regulatory networks underlying development is to obtain comprehensive information on gene expression. In this study, we measured expression profiles for the entire expressed gene set during sea urchin embryonic development. We confirmed the reliability of these profiles by comparison with NanoString measurements for a subset of genes and with literature values. The data show that ~16,500 genes have been activated by the end of embryogenesis, and for half of them the transcript abundance changes more than 10-fold during development. From this genome scale expression survey, we show that complex patterns of expression by many genes underlie embryonic development, particularly during the early stages before gastrulation. An intuitive web application for data query and visualization is presented to facilitate use of this large dataset.

PubMed ID: 24291147
PMC ID: PMC3898891
Article link: Dev Biol
Grant support: [+]

Genes referenced: LOC100887844 LOC115925415 LOC583082

References [+] :
Bruskin, Accumulation in embryogenesis of five mRNAs enriched in the ectoderm of the sea urchin pluteus. 1981, Pubmed, Echinobase