Click here to close Hello! We notice that you are using Internet Explorer, which is not supported by Echinobase and may cause the site to display incorrectly. We suggest using a current version of Chrome, FireFox, or Safari.
Echinobase
ECB-ART-49211
Int J Mol Sci 2021 Apr 09;228:. doi: 10.3390/ijms22083882.
Show Gene links Show Anatomy links

Comparative Transcriptomes of the Body Wall of Wild and Farmed Sea Cucumber Isostichopus badionotus.

Martín-Hernández R , Rodríguez-Canul R , Kantún-Moreno N , Olvera-Novoa MA , Medina-Contreras O , Garikoitz-Legarda C , Triviño JC , Zamora-Briseño JA , May-Solis V , Poot-Salazar A , Pérez-Vega JA , Gil-Zamorano J , Grant G , Dávalos A , Olivera-Castillo L .


Abstract
Overfishing of sea cucumber Isostichopus badionotus from Yucatan has led to a major population decline. They are being captured as an alternative to traditional species despite a paucity of information about their health-promoting properties. The transcriptome of the body wall of wild and farmed I. badionotus has now been studied for the first time by an RNA-Seq approach. The functional profile of wild I. badionotus was comparable with data in the literature for other regularly captured species. In contrast, the metabolism of first generation farmed I. badionotus was impaired. This had multiple possible causes including a sub-optimal growth environment and impaired nutrient utilization. Several key metabolic pathways that are important in effective handling and accretion of nutrients and energy, or clearance of harmful cellular metabolites, were disrupted or dysregulated. For instance, collagen mRNAs were greatly reduced and deposition of collagen proteins impaired. Wild I. badionotus is, therefore, a suitable alternative to other widely used species but, at present, the potential of farmed I. badionotus is unclear. The environmental or nutritional factors responsible for their impaired function in culture remain unknown, but the present data gives useful pointers to the underlying problems associated with their aquaculture.

PubMed ID: 33918680
PMC ID: PMC8070510
Article link: Int J Mol Sci
Grant support: [+]



Article Images: [+] show captions
References [+] :
Boyko, The Eupentacta fraudatrix transcriptome provides insights into regulation of cell transdifferentiation. 2020, Pubmed, Echinobase