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XB-PHENO-27292

Xtr Wt + lamb4 CRISPR, Edwards NA et al. (2025)

Experiment + Assay: Xtr Wt + lamb4 CRISPR + NF44 (immunohistochemistry)
Background: Xtr.Outbred
Manipulations:
Manipulation Type Reagent Target Gene Stage Treatment Area
CRISPR lamb4 gRNA1 lamb4
 NF stage 1 whole organism
Conditions:
Assay Type Assay Stages Antibody
immunohistochemistry NF stage 44  
Anatomical Phenotypes: abnormal esophagus morphology, abnormal trachea morphology, abnormal tracheoesophageal septum
Human Disease Associations: esophageal atresia, esophageal atresia/tracheoesophageal fistula
Source: Fig. 2 r2c3
Article: XB-ART-61390, PubMed