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XB-PHENO-25957

Xla Wt + tp53rk MO, Treimer E et al. (2022)

Experiment + Assay: Xla Wt + tp53rk MO + NF45 (whole-mount microscopy)
Background: Xla.Outbred
Manipulations:
Manipulation Type Reagent Target Gene Stage Treatment Area
morpholino injection tp53rk MO1 tp53rk (Xla)
NF stage 8 dorsal animal hemisphere blastomere
Conditions:
Assay Type Assay Stages Antibody
whole-mount microscopy NF stage 45  
Anatomical Phenotypes: abnormal cartilage tissue, abnormal eye morphology, abnormal head morphology, decreased size of the eye, decreased size of the head
Human Disease Associations: Galloway-Mowat syndrome 1, microphthalmia
Source: Fig. S2 ABCDEF
Article: XB-ART-59342, PubMed