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XB-PHENO-24598

Xla Wt + six1-R110W, Mehdizadeh T et al. (2021)

Experiment + Assay: Xla Wt + six1-R110W + NF26-32 (head-qPCR)
Background: Xla.Outbred
Manipulations:
Manipulation Type Reagent Target Gene Stage Treatment Area
mRNA injection Tg(six1-R110W) six1 (Xla)
 NF stage 4 (8-cell) animal blastomere
Conditions:
Assay Type Assay Stages Antibody
Other Detection Assay NF stage 26 to NF stage 32  
Expression Phenotypes (4):
decreased amount eya2.L expression in head
decreased amount pa2g4.L expression in head
decreased amount prdm1.L expression in head
decreased amount tspan13.L expression in head
Human Disease Associations: branchiootorenal syndrome
Source: Fig. 3B (black)
Article: XB-ART-58245, PubMed