Click here to close Hello! We notice that you are using Internet Explorer, which is not supported by Xenbase and may cause the site to display incorrectly. We suggest using a current version of Chrome, FireFox, or Safari.

Summary Attributions Wiki
XB-GRNA-25900333

gRNA Name: itgb4 gRNA1
Synonyms: Xt.itgb4 gRNA
Genomic Target: itgb4

Sequence: 5' AAACACATTCAGGTCAAATG 3'



Genomic Target tropicalis
Identities 20/20
genome
gRNA
5' CATTTGACCTGAATGTGTTT 3'
   ||||||||||||||||||||
3' GTAAACTGGACTTACACAAA 5'
     
Genomic Alignments Position Identity Strand Target Genomic Target
laevis 10.1 Chr4L:38673774..38673793 19/20 Sense off-target znf423.L
Chr6L:44485258..44485277 18/20 Antisense off-target cpvl.L
Chr6L:24663315..24663334 18/20 Antisense off-target myo3a.L
Chr9_10S:29663646..29663665 18/20 Sense off-target rbfox3.S
Chr9_10L:33277132..33277151 18/20 Antisense off-target LOC108701017
Chr2L:25082720..25082739 17/20 Sense off-target robo2.L
Chr7S:17027013..17027032 17/20 Sense off-target adgra1.S
Chr2S:120261270..120261289 17/20 Sense off-target LOC108709778
Chr2L:115526224..115526243 19/20 Antisense unknown
Chr1S:197217618..197217637 18/20 Antisense unknown
Chr8S:88399491..88399510 18/20 Antisense unknown
Chr8S:88703454..88703473 18/20 Antisense unknown
Chr6S:69537565..69537584 17/20 Antisense unknown
Chr4L:58534230..58534249 17/20 Sense unknown
Chr6L:82299633..82299652 16/20 Sense unknown
tropicalis 10.0 Chr10:44741214..44741233 20/20 Antisense target itgb4
Chr7:90356267..90356286 17/20 Antisense off-target plch2
Chr3:47250801..47250820 17/20 Sense unknown
Publications
???morpholino.displaySummary.papersFirst??? Identification and validation of candidate risk genes in endocytic vesicular trafficking associated with esophageal atresia and tracheoesophageal fistulas., HGG Adv 2022     
???morpholino.displaySummary.papersRecent??? Disrupted endosomal trafficking of the Vangl-Celsr polarity complex underlies congenital anomalies in Xenopus trachea-esophageal morphogenesis., Dev Cell 2025     
???morpholino.displaySummary.papersAll???