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Summary Attributions Wiki
XB-GRNA-23659147
gRNA Name: sox2 gRNA1
Synonyms:
Genomic Target: sox2

PAM Sequence: AGG
Sequence: 5' TGGTATGGTCCAGGGGCCAG 3'



Genomic Target tropicalis laevis.L
Identities 20/20 20/20
genome
gRNA
 
5' CTGGCCCCTGGACCATACCA 3'
   ||||||||||||||||||||
3' GACCGGGGACCTGGTATGGT 5'
 
5' CTGGCCCCTGGACCATACCA 3'
   ||||||||||||||||||||
3' GACCGGGGACCTGGTATGGT 5'
     
Genomic Alignments Position Identity Strand Target Genomic Target
laevis 9.2 Scaffold33547:574..593 20/20 Antisense target sox2.L
chr2L:115362207..115362226 19/20 Antisense off-target sox1.L
chr3L:39088585..39088604 17/20 Antisense unknown
tropicalis 10.0 Chr5:108037294..108037313 20/20 Antisense target sox2
Chr3:51927364..51927383 16/20 Antisense off-target avpr1a
Chr3:109502565..109502584 16/20 Sense off-target LOC116409779
Chr4:147508789..147508808 19/20 Sense unknown
Chr7:37741897..37741916 17/20 Antisense unknown
Publications
???morpholino.displaySummary.papersFirst??? Maximizing CRISPR/Cas9 phenotype penetrance applying predictive modeling of editing outcomes in Xenopus and zebrafish embryos., Sci Rep 2020     
???morpholino.displaySummary.papersRecent??? Disrupted endosomal trafficking of the Vangl-Celsr polarity complex underlies congenital anomalies in Xenopus trachea-esophageal morphogenesis., Dev Cell 2025     
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