Click here to close Hello! We notice that you are using Internet Explorer, which is not supported by Echinobase and may cause the site to display incorrectly. We suggest using a current version of Chrome, FireFox, or Safari.
Echinobase

Summary Attributions Wiki
ECB-MORPHOLINO-24506009
Morpholino Name: lefty1 MO2
Synonyms: Lefty Mo1, lefty-Mo
Target mRNA: lefty1
Derived from:

Morpholino Type: translation blocking morpholino
Sequence: 5' GGAGCGCCATGAGATAATTCCATAT 3'

Source: Gene Tools LLC


Target mRNA S. purpuratus L. variegatus
Identities 21/25 22/25
genome
MO
 
5' ATATGGAATTATCACTCGGTGCTCC 3'
   ||||||||||||| |  || |||||
3' TATACCTTAATAGAGTACCGCGAGG 5'
 
5' ATATGGAATTATCACTTGGTGCTCC 3'
   ||||||||||||| | ||| |||||
3' TATACCTTAATAGAGTACCGCGAGG 5'
     
Genomic Alignments Position Identity Strand Target Target mRNA
S. purpuratus 5.0 NW_022145611.1:15747149..15747173 21/25 Antisense target lefty1
L. variegatus 3.0 chr7:627320..627344 22/25 Antisense target lefty1
Publications
???morpholino.displaySummary.papersFirst??? Ancestral regulatory circuits governing ectoderm patterning downstream of Nodal and BMP2/4 revealed by gene regulatory network analysis in an echinoderm., PLoS Genet 2010                        
???morpholino.displaySummary.papersRecent??? MAPK and GSK3/ß-TRCP-mediated degradation of the maternal Ets domain transcriptional repressor Yan/Tel controls the spatial expression of nodal in the sea urchin embryo., PLoS Genet 2018                  
???morpholino.displaySummary.papersAll???