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J Fungi (Basel)
2020 Oct 16;64:. doi: 10.3390/jof6040229.
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Metabolites from Clonostachys Fungi and Their Biological Activities.
Han P
,
Zhang X
,
Xu D
,
Zhang B
,
Lai D
,
Zhou L
.
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Clonostachys (teleomorph: Bionectria) fungi are well known to produce a variety of secondary metabolites with various biological activities to show their pharmaceutical and agrochemical applications. Up to now, at least 229 secondary metabolites, mainly including 84 nitrogen-containing metabolites, 85 polyketides, 40 terpenoids, and 20 other metabolites, have been reported. Many of these compounds exhibit biological activities, such as cytotoxic, antimicrobial, antileishmanial, antimalarial activities. This mini-review aims to summarize the diversity of the secondary metabolites as well as their occurrences in Clonostachys fungi and biological activities.
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