Click
here to close Hello! We notice that
you are using Internet Explorer, which is not supported by Echinobase
and may cause the site to display incorrectly. We suggest using a
current version of Chrome,
FireFox,
or Safari.
???displayArticle.abstract???
Background and Objectives: The aim of this retrospective cohort study was to search individual, sociodemographic and environmental predictors of COVID-19 outcomes. Materials and Methods: A convenience sample of 1036 COVID-19 confirmed patients (3-99 years, mean 59 years; 482 females) who sought treatment at the emergency units of the public health system of Diadema (Brazil; March-October 2020) was included. Primary data were collected from medical records: sex, age, occupation/education, onset of symptoms, presence of chronic diseases/treatment and outcome (death and non-death). Secondary socioeconomic and environmental data were provided by the Department of Health. Results: The mean time spent between COVID-19 symptom onset and admission to the health system was 7.4 days. Principal component analysis summarized secondary sociodemographic data, and a Poisson regression model showed that the time between symptom onset and health system admission was higher for younger people and those from the least advantaged regions (availability of electricity, a sewage network, a water supply and garbage collection). A multiple logistic regression model showed an association of age (OR = 1.08; 1.05-1.1), diabetes (OR = 1.9; 1.1-3.4) and obesity (OR = 2.9; 1.1-7.6) with death outcome, while hypertension and sex showed no significant association. Conclusion: The identification of vulnerable groups may help the development of health strategies for the prevention and treatment of COVID-19.
CAPES/ Finance Code 001 The first author received scholarship from the Coordenação de Aperfeiçoamento de Pessoal de Nível Superior, Brazil (Coordination for the Improvement of Higher Education Personnel)
Arcaya,
Inequalities in health: definitions, concepts, and theories.
2015, Pubmed
Arcaya,
Inequalities in health: definitions, concepts, and theories.
2015,
Pubmed
Barek,
Impact of age, sex, comorbidities and clinical symptoms on the severity of COVID-19 cases: A meta-analysis with 55 studies and 10014 cases.
2020,
Pubmed
Barreto,
Successes and failures in the control of infectious diseases in Brazil: social and environmental context, policies, interventions, and research needs.
2011,
Pubmed
Booth,
Population risk factors for severe disease and mortality in COVID-19: A global systematic review and meta-analysis.
2021,
Pubmed
Burström,
Social determinants of health and inequalities in COVID-19.
2020,
Pubmed
Codo,
Elevated Glucose Levels Favor SARS-CoV-2 Infection and Monocyte Response through a HIF-1α/Glycolysis-Dependent Axis.
2020,
Pubmed
Corona,
Diabetes is most important cause for mortality in COVID-19 hospitalized patients: Systematic review and meta-analysis.
2021,
Pubmed
Dhochak,
Pathophysiology of COVID-19: Why Children Fare Better than Adults?
2020,
Pubmed
Estrela,
Covid-19 Pandemic: reflecting vulnerabilities in the light of gender, race and class.
2020,
Pubmed
Gasmi,
Interrelations between COVID-19 and other disorders.
2021,
Pubmed
Gregor,
Inflammatory mechanisms in obesity.
2011,
Pubmed
Hu,
Characteristics of SARS-CoV-2 and COVID-19.
2021,
Pubmed
Huang,
Clinical features of patients infected with 2019 novel coronavirus in Wuhan, China.
2020,
Pubmed
Khalatbari-Soltani,
Importance of collecting data on socioeconomic determinants from the early stage of the COVID-19 outbreak onwards.
2020,
Pubmed
Knapp,
Diabetes and infection: is there a link?--A mini-review.
2013,
Pubmed
Landecho,
Obesity as an adipose tissue dysfunction disease and a risk factor for infections - Covid-19 as a case study.
2021,
Pubmed
Lee,
COVID-19 Amplifiers on Health Inequity Among the Older Populations.
2020,
Pubmed
Lim,
COVID-19 and diabetes mellitus: from pathophysiology to clinical management.
2021,
Pubmed
Malik,
Obesity a predictor of outcomes of COVID-19 hospitalized patients-A systematic review and meta-analysis.
2021,
Pubmed
Peres,
Sociodemographic factors associated with COVID-19 in-hospital mortality in Brazil.
2021,
Pubmed
Pierce,
Immune responses to SARS-CoV-2 infection in hospitalized pediatric and adult patients.
2020,
Pubmed
Rebello,
Obesity, the most common comorbidity in SARS-CoV-2: is leptin the link?
2020,
Pubmed
Ritter,
Obesity and COVID-19: Molecular Mechanisms Linking Both Pandemics.
2020,
Pubmed
Simonnet,
High Prevalence of Obesity in Severe Acute Respiratory Syndrome Coronavirus-2 (SARS-CoV-2) Requiring Invasive Mechanical Ventilation.
2020,
Pubmed
Sohrabi,
Sociodemographic determinants and clinical risk factors associated with COVID-19 severity: a cross-sectional analysis of over 200,000 patients in Tehran, Iran.
2021,
Pubmed
Vilar-Compte,
Urban poverty and nutrition challenges associated with accessibility to a healthy diet: a global systematic literature review.
2021,
Pubmed
Wang,
Clinical progression and outcomes of 260 patients with severe COVID-19: an observational study.
2021,
Pubmed