Click here to close Hello! We notice that you are using Internet Explorer, which is not supported by Echinobase and may cause the site to display incorrectly. We suggest using a current version of Chrome, FireFox, or Safari.
Echinobase
ECB-ART-47341
Nat Prod Res 2021 Jun 01;3511:1928-1932. doi: 10.1080/14786419.2019.1644633.
Show Gene links Show Anatomy links

Antitumor activity of saponin isolated from the sea cucumber, holothuria arenicola against ehrlich ascites carcinoma cells in swiss albino mice.

Mohamed AS , Mahmoud SA , Soliman AM , Fahmy SR .


???displayArticle.abstract???
The present investigation attempted study the potential use of the Holothuria arenicola saponin (HaS) against Ehrlich Ascites Carcinoma (EAC) tumor model in female Swiss albino mice. The HPLC studies of the extracted saponin showed the peak at retention time 5.19 min. was is matched with the standard saponin with total amount 34.87%. Significant improvements were detected in the tumor markers, complete blood count, antioxidant system, liver function and kidney function of HaS-treated mice. The present study demonstrated that HaS is a potent natural product that has promising antineoplastic efficacy.

???displayArticle.pubmedLink??? 31343268
???displayArticle.link??? Nat Prod Res


Genes referenced: LOC100887844