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Summary Expression Gene Literature (3348) GO Terms (0) Nucleotides (11) Proteins (3) Interactants (395) Wiki

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Sedoheptulose kinase bridges the pentose phosphate pathway and immune responses in pathogen-challenged sea cucumber Apostichopus japonicus., Sun L, Zhou F, Shao Y, Lv Z, Li C., Dev Comp Immunol. April 10, 2020; 103694.

Echinochrome Exhibits Antitumor Activity against Ehrlich Ascites Carcinoma in Swiss Albino Mice., Mohamed AS., Nutr Cancer. March 9, 2020; 1-9.

Expression and purification of recombinant mouse CRISP4 using a baculovirus system., Gaikwad AS, Lee Loh K, O'Connor AE, Reid HH, O'Bryan MK., Protein Expr Purif. March 1, 2020; 167 105543.

Two different fucosylated chondroitin sulfates: Structural elucidation, stimulating hematopoiesis and immune-enhancing effects., Niu Q, Li G, Li C, Li Q, Li J, Liu C, Pan L, Li S, Cai C, Hao J, Yu G., Carbohydr Polym. February 15, 2020; 230 115698.

Bicistronic transfer of CDKN2A and p53 culminates in collaborative killing of human lung cancer cells in vitro and in vivo., Xande JG, Dias AP, Tamura RE, Cruz MC, Brito B, Ferreira RA, Strauss BE, Costanzi-Strauss E., Gene Ther. February 1, 2020; 27 (1-2): 51-61.

Comparisons of protective effects between two sea cucumber hydrolysates against diet induced hyperuricemia and renal inflammation in mice., Wan H, Han J, Tang S, Bao W, Lu C, Zhou J, Ming T, Li Y, Su X., Food Funct. January 29, 2020; 11 (1): 1074-1086.

Inflammasome activation and IL-1 signaling during placental malaria induce poor pregnancy outcomes., Reis AS, Barboza R, Murillo O, Barateiro A, Peixoto EPM, Lima FA, Gomes VM, Dombrowski JG, Leal VNC, Araujo F, Bandeira CL, Araujo RBD, Neres R, Souza RM, Costa FTM, Pontillo A, Bevilacqua E, Wrenger C, Wunderlich G, Palmisano G, Labriola L, Bortoluci KR, Penha-Gonçalves C, Gonçalves LA, Epiphanio S, Marinho CRF., Sci Adv. January 1, 2020; 6 (10): eaax6346.

p19Arf sensitizes B16 melanoma cells to interferon-β delivered via mesenchymal stem cells in vitro., Da-Costa RC, Vieira IL, Hunger A, Tamura RE, Strauss BE., Braz J Med Biol Res. January 1, 2020; 53 (3): e8876.

EF-hand like Region in the N-terminus of Anoctamin 1 Modulates Channel Activity by Ca2+ and Voltage., Tak MH, Jang Y, Son WS, Yang YD, Oh U., Exp Neurobiol. December 31, 2019; 28 (6): 658-669.

Fucoidan from sea cucumber Holothuria polii: Structural elucidation and stimulation of hematopoietic activity., Li C, Niu Q, Li S, Zhang X, Liu C, Cai C, Li G, Yu G., Int J Biol Macromol. November 18, 2019;

Structures and Bioactivities of Psolusosides B1, B2, J, K, L, M, N, O, P, and Q from the Sea Cucumber Psolus fabricii. The First Finding of Tetrasulfated Marine Low Molecular Weight Metabolites., Silchenko AS, Kalinovsky AI, Avilov SA, Kalinin VI, Andrijaschenko PV, Dmitrenok PS, Popov RS, Chingizova EA., Mar Drugs. November 6, 2019; 17 (11):

Gut microbial metabolite butyrate protects against proteinuric kidney disease through epigenetic- and GPR109a-mediated mechanisms., Felizardo RJF, de Almeida DC, Pereira RL, Watanabe IKM, Doimo NTS, Ribeiro WR, Cenedeze MA, Hiyane MI, Amano MT, Braga TT, Ferreira CM, Parmigiani RB, Andrade-Oliveira V, Volpini RA, Vinolo MAR, Mariño E, Robert R, Mackay CR, Camara NOS., FASEB J. November 1, 2019; 33 (11): 11894-11908.

Modulation of Doxorubicin Intracellular Accumulation and Anticancer Activity by Triterpene Glycoside Cucumarioside A2-2., Menchinskaya E, Gorpenchenko T, Silchenko A, Avilov S, Aminin D., Mar Drugs. October 23, 2019; 17 (11):         

The regulation of the sulfur amino acid biosynthetic pathway in Cryptococcus neoformans: the relationship of Cys3, Calcineurin, and Gpp2 phosphatases., de Melo AT, Martho KF, Roberto TN, Nishiduka ES, Machado J, Brustolini OJB, Tashima AK, Vasconcelos AT, Vallim MA, Pascon RC., Sci Rep. August 15, 2019; 9 (1): 11923.                

Long-Chain Bases from Sea Cucumber Alleviate Obesity by Modulating Gut Microbiota., Hu S, Xu Y, Gao X, Li S, Jiang W, Liu Y, Su L, Yang H., Mar Drugs. August 1, 2019; 17 (8):             

Structures of three ependymin-related proteins suggest their function as a hydrophobic molecule binder., Park JK, Kim KY, Sim YW, Kim YI, Kim JK, Lee C, Han J, Kim CU, Lee JE, Park S., IUCrJ. July 1, 2019; 6 (Pt 4): 729-739.            

Malaria infection promotes a selective expression of kinin receptors in murine liver., Ventura PDS, Carvalho CPF, Barros NMT, Martins-Silva L, Dantas EO, Martinez C, Melo PMS, Pesquero JB, Carmona AK, Nagaoka MR, Gazarini ML., Malar J. June 24, 2019; 18 (1): 213.          

Structures and Bioactivities of Six New Triterpene Glycosides, Psolusosides E, F, G, H, H1, and I and the Corrected Structure of Psolusoside B from the Sea Cucumber Psolus fabricii., Silchenko AS, Kalinovsky AI, Avilov SA, Kalinin VI, Andrijaschenko PV, Dmitrenok PS, Popov RS, Chingizova EA, Ermakova SP, Malyarenko OS., Mar Drugs. June 14, 2019; 17 (6):       

Hepatoprotective Effect of Seed Coat ofEuryale ferox Extract in Non-alcoholic Fatty Liver Disease Induced by High-fat Diet in Mice by Increasing IRs-1 and Inhibiting CYP2E1., Jian T, Yu C, Ding X, Chen J, Li J, Zuo Y, Ren B, Lv H, Li W., J Oleo Sci. June 6, 2019; 68 (6): 581-589.

Pharmacological characterization of JWX-A0108 as a novel type I positive allosteric modulator of α7 nAChR that can reverse acoustic gating deficits in a mouse prepulse inhibition model., Sun LL, Yang TY, Wei NN, Lu W, Jiao WX, Zhou QQ, Miao YZ, Gao Q, Wang XT, Sun Q, Wang K., Acta Pharmacol Sin. June 1, 2019; 40 (6): 737-745.

Sea Cucumber (Stichopus japonicas) F2 Enhanced TRAIL-Induced Apoptosis via XIAP Ubiquitination and ER Stress in Colorectal Cancer Cells., Kim JL, Park SH, Jeong S, Kim BR, Na YJ, Jo MJ, Jeong YA, Yun HK, Kim DY, Kim BG, You S, Oh SC, Lee DH., Nutrients. May 11, 2019; 11 (5):             

Golden sea cucumber extract revives glucose transporter-4 and interleukin-6 protein level in diabetic mouse muscle., Purwanto B, Wiyasihati SI, Masyitha PA, Wigati KW, Irwadi I., Vet World. May 1, 2019; 12 (5): 684-688.  

Combination of cabazitaxel and p53 gene therapy abolishes prostate carcinoma tumor growth., Tamura RE, Lana MG, Costanzi-Strauss E, Strauss BE., Gene Ther. March 29, 2019;

cAMP binds to closed, inactivated, and open sea urchin HCN channels in a state-dependent manner., Idikuda V, Gao W, Su Z, Liu Q, Zhou L., J Gen Physiol. February 4, 2019; 151 (2): 200-213.              

OVA-Induced Allergic Airway Inflammation Mouse Model., Casaro M, Souza VR, Oliveira FA, Ferreira CM., Methods Mol Biol. January 1, 2019; 1916 297-301.

Co-option of the PRDM14-CBFA2T complex from motor neurons to pluripotent cells during vertebrate evolution., Kawaguchi M, Sugiyama K, Matsubara K, Lin CY, Kuraku S, Hashimoto S, Suwa Y, Yong LW, Takino K, Higashida S, Kawamura D, Yu JK, Seki Y., Development. January 1, 2019; 146 (2):

Efficient oral vaccination by bioengineering virus-like particles with protozoan surface proteins., Serradell MC, Rupil LL, Martino RA, Prucca CG, Carranza PG, Saura A, Fernández EA, Gargantini PR, Tenaglia AH, Petiti JP, Tonelli RR, Reinoso-Vizcaino N, Echenique J, Berod L, Piaggio E, Bellier B, Sparwasser T, Klatzmann D, Luján HD., Nat Commun. January 1, 2019; 10 (1): 361.            

Fetal-Derived MyD88 Signaling Contributes to Poor Pregnancy Outcomes During Gestational Malaria., Barboza R, Hasenkamp L, Barateiro A, Murillo O, Peixoto EPM, Lima FA, Reis AS, Gonçalves LA, Epiphanio S, Marinho CRF., Front Microbiol. January 1, 2019; 10 68.        

Analysis of sea star larval regeneration reveals conserved processes of whole-body regeneration across the metazoa., Cary GA, Cary GA, Wolff A, Zueva O, Pattinato J, Hinman VF., BMC Biol. January 1, 2019; 17 (1): 16.                  

In vitro and in vivo Induction of p53-Dependent Apoptosis by Extract of Euryale ferox Salisb in A549 Human Caucasian Lung Carcinoma Cancer Cells Is Mediated Through Akt Signaling Pathway., Nam GH, Jo KJ, Park YS, Kawk HW, Kim SY, Kim YM., Front Oncol. January 1, 2019; 9 406.            

Comparative genomic analysis suggests that the sperm-specific sodium/proton exchanger and soluble adenylyl cyclase are key regulators of CatSper among the Metazoa., Romero F, Nishigaki T., Zoological Lett. January 1, 2019; 5 25.            

CNEr: A toolkit for exploring extreme noncoding conservation., Tan G, Polychronopoulos D, Lenhard B., PLoS Comput Biol. January 1, 2019; 15 (8): e1006940.              

The evolution of a new cell type was associated with competition for a signaling ligand., Ettensohn CA, Adomako-Ankomah A., PLoS Biol. January 1, 2019; 17 (9): e3000460.                    

GLIPR1L1 is an IZUMO-binding protein required for optimal fertilization in the mouse., Gaikwad AS, Anderson AL, Merriner DJ, O'Connor AE, Houston BJ, Aitken RJ, O'Bryan MK, Nixon B., BMC Biol. January 1, 2019; 17 (1): 86.                    

Comparative electrophysiological analysis of the bile acid-sensitive ion channel (BASIC) from different species suggests similar physiological functions., Lenzig P, Wirtz M, Wiemuth D., Pflugers Arch. January 1, 2019; 471 (2): 329-336.

iProteinDB: An Integrative Database of Drosophila Post-translational Modifications., Hu Y, Sopko R, Chung V, Foos M, Studer RA, Landry SD, Liu D, Rabinow L, Gnad F, Beltrao P, Perrimon N., G3 (Bethesda). January 1, 2019; 9 (1): 1-11.

Anticipation of food intake induces phosphorylation switch to regulate basolateral amino acid transporter LAT4 (SLC43A2) function., Oparija L, Rajendran A, Poncet N, Verrey F., J Physiol. January 1, 2019; 597 (2): 521-542.

Functional characterization of Cynoglossus semilaevis R-spondin2 and its role in muscle development during embryogenesis., Wang B, Yang F, Li R, Li X, Wu X, Sun Z, Zhai J, He Y, Qi J., Genes Genet Syst. December 22, 2018; 93 (5): 181-190.

Magneto low-density nanoemulsion (MLDE): A potential vehicle for combined hyperthermia and photodynamic therapy to treat cancer selectively., Pellosi DS, Macaroff PP, Morais PC, Tedesco AC., Mater Sci Eng C Mater Biol Appl. November 1, 2018; 92 103-111.

Fungal Immunomodulatory Protein from Nectria haematococca Suppresses Growth of Human Lung Adenocarcinoma by Inhibiting the PI3K/Akt Pathway., Xie Y, Li S, Sun L, Liu S, Wang F, Wen B, Sun L, Fang X, Chai Y, Cao H, Jia N, Gu T, Lou X, Xin F., Int J Mol Sci. November 1, 2018; 19 (11):             

Calcium Signaling in Vertebrate Development and Its Role in Disease., Paudel S, Sindelar R, Saha M., Int J Mol Sci. October 30, 2018; 19 (11):

Cladolosides C4, D1, D2, M, M1, M2, N and Q, new triterpene glycosides with diverse carbohydrate chains from sea cucumber Cladolabes schmeltzii. An uncommon 20,21,22,23,24,25,26,27-okta-nor-lanostane aglycone. The synergism of inhibitory action of non-toxic dose of the glycosides and radioactive irradiation on colony formation of HT-29 cancer cells., Silchenko AS, Kalinovsky AI, Avilov SA, Andryjaschenko PV, Dmitrenok PS, Yurchenko EA, Ermakova SP, Malyarenko OS, Dolmatov IY, Kalinin VI., Carbohydr Res. October 1, 2018; 468 36-44.

Cladolosides O, P, P1-P3 and R, triterpene glycosides with two novel types of carbohydrate chains from the sea cucumberCladolabes schmeltzii. Inhibition of cancer cells colony formation and its synergy with radioactive irradiation., Silchenko AS, Kalinovsky AI, Avilov SA, Andryjaschenko PV, Dmitrenok PS, Yurchenko EA, Ermakova SP, Malyarenko OS, Dolmatov IY, Kalinin VI., Carbohydr Res. October 1, 2018; 468 73-79.

Potential use of compounds from sea cucumbers as MDM2 and CXCR4 inhibitors to control cancer cell growth., Wargasetia TL, Permana S, Widodo N., Exp Ther Med. October 1, 2018; 16 (4): 2985-2991.          

Non-polar compounds of Persian Gulf sea cucumber Holothuria parva selectively induce toxicity on skin mitochondria isolated from animal model of melanoma., Arast Y, Seyed Razi N, Nazemi M, Seydi E, Pourahmad J., Cutan Ocul Toxicol. September 1, 2018; 37 (3): 218-227.

A Novel Atypical PKC-Iota Inhibitor, Echinochrome A, Enhances Cardiomyocyte Differentiation from Mouse Embryonic Stem Cells., Kim HK, Cho SW, Heo HJ, Jeong SH, Kim M, Ko KS, Rhee BD, Mishchenko NP, Vasileva EA, Fedoreyev SA, Stonik VA, Han J., Mar Drugs. June 2, 2018; 16 (6):             

Prophylactic Bifidobacterium adolescentis ATTCC 15703 supplementation reduces partially allergic airway disease in Balb/c but not in C57BL/6 mice., Casaro MC, Crisma AR, Vieira AT, Silva GHM, Mendes E, Ribeiro WR, Martins FS, Ferreira CM., Benef Microbes. April 25, 2018; 9 (3): 465-476.

Combining In Vivo and In Vitro Approaches To Identify Human Odorant Receptors Responsive to Food Odorants., Armelin-Correa LM, Malnic B., J Agric Food Chem. March 14, 2018; 66 (10): 2214-2218.

The Anti-Cancer Effects of Frondoside A., Adrian TE, Collin P., Mar Drugs. February 19, 2018; 16 (2):   

In vitro and in vivo anti-leukemic effects of cladoloside C2 are mediated by activation of Fas/ceramide synthase 6/p38 kinase/c-Jun NH2-terminal kinase/caspase-8., Yun SH, Sim EH, Han SH, Kim TR, Ju MH, Han JY, Jeong JS, Kim SH, Silchenko AS, Stonik VA, Park JI., Oncotarget. January 2, 2018; 9 (1): 495-511.                

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