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ECB-ANTIBODY-26396198

Antibody Name: sptan1 Ab2

Common Name: spectrin alpha, non-erythrocytic 1

RRID:
Synonyms: alpha-spectrin, egg spectrin

Antigens
Gene: sptan1

Clone Type: Polyclonal
Source:

Antibody
Clone Number
Purification Affinity Purification
Isotype isotype unknown
Host Organism rabbit
Echinoderm Reactivity L. variegatus, S. purpuratus, P. miniata, L. pictus
Non-Echinoderm Reactivity
Description: Reacts with a ~240 kDa egg protein that localizes to the plasma membrane and various cytoplasmic vesicular membranes. Created using rabbit no. 7 and previously supplied by Dr. Douglas Fishkind (Worcester Foundation for Experimental Biology, Shrewsbury, Massachusetts) and Dr. David Begg (Harvard Medical School, Boston, Massachusetts). Also reacts with Arbacia punctulata, Strongylocentrotus droebachiensis, Thyone briareus, and Tripneustes gratilla.
Immunogen
Name Egg Spectrin
Type polypeptide
Post Translational Modifications None
Source Organism purple sea urchin
Description Native protein electrophoretically purified from sea urchin eggs.
Sequence
Reported Usage
immunofluorescence
immunoprecipitation
western blot
Publications
???displayAntibody.papersFirst??? The cortical actin-membrane cytoskeleton of unfertilized sea urchin eggs: analysis of the spatial organization and relationship of filamentous actin, nonfilamentous actin, and egg spectrin., Dev Biol 1989  
???displayAntibody.papersRecent??? Alteration of cell cycle timing and induction of surface instability in starfish blastomeres microinjected with antibodies to spectrin., Dev Biol 1996  
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