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ECB-ANTIBODY-26396102
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Antibody Name:
duox1 Ab3
Common Name: dual oxidase 1 RRID: Synonyms: Udx1, urchin dual oxidase 1
Source: |
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| Antibody | |
| Clone Number | |
| Purification | Affinity Purification |
| Isotype | IgG |
| Host Organism | rabbit |
| Echinoderm Reactivity | S. purpuratus |
| Non-Echinoderm Reactivity | |
| Description: | Function-blocking antibody that reacts with a ~185 kDa cell surface protein and has been demonstrated to inhibit hydrogen peroxide production in fertilized sea urchin eggs. Created by the Wessel lab at Brown University in Providence, Rhode Island. Also reacts with Lytechinus variegatus. |
| Immunogen | |
| Name | Udx1 NADPH |
| Type | polypeptide |
| Post Translational Modifications | None |
| Source Organism | variegated sea urchin |
| Description | Recombinant protein containing amino acid residues 1345 to 1624 (RKKAE...HHFEN), corresponding to the C-terminal cytoplasmic NADPH-binding domain. NCBI Accession #: AAU95793. |
| Sequence | |
| Reported Usage | |
| immunofluorescence | |
| western blot | |
| Publications | |
| ???displayAntibody.papersFirst??? |
The oxidative burst at fertilization is dependent upon activation of the dual oxidase Udx1., Dev Cell 2004 |
| ???displayAntibody.papersRecent??? |
Reactive oxygen species and Udx1 during early sea urchin development., Dev Biol 2005 |
| ???displayAntibody.papersAll??? | |