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Echinobase

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ECB-ANTIBODY-26396055

Antibody Name: hsp110 Ab1

Common Name: egg receptor for sperm

RRID:
Synonyms: 350-kDa sperm receptor protein, 70KL

Antigens
Gene: hsp110

Clone Type: Polyclonal
Source:

Antibody
Clone Number
Purification Affinity Purification
Isotype IgG
Host Organism rabbit
Echinoderm Reactivity S. purpuratus
Non-Echinoderm Reactivity
Description: Species-specific antibody demonstrated to inhibit sperm binding and subsequent fertilization by reacting with a plasma membrane receptor within purple sea urchin eggs. Created by K. R. Foltz and W. J. Lennarz (State University of New York at Stony Brook).
Immunogen
Name 70-kD LysC Fragment
Type polypeptide
Post Translational Modifications Glycosylation
Source Organism purple sea urchin
Description Extracellular glycoprotein region prepared using DEAE-chromatography on crude egg proteins digested using lysylendoproteinase C.
Sequence
Reported Usage
immunofluorescence
immunoprecipitation
western blot
immunohistochemistry
Publications
???displayAntibody.papersFirst??? Identification of the sea urchin egg receptor for sperm using an antiserum raised against a fragment of its extracellular domain., J Cell Biol 1992  
???displayAntibody.papersRecent??? Surface localization of the sea urchin egg receptor for sperm., Dev Biol 1997  
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