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ECB-ANTIBODY-26396055
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Antibody Name:
hsp110 Ab1
Common Name: egg receptor for sperm RRID: Synonyms: 350-kDa sperm receptor protein, 70KL
Source: |
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| Antibody | |
| Clone Number | |
| Purification | Affinity Purification |
| Isotype | IgG |
| Host Organism | rabbit |
| Echinoderm Reactivity | S. purpuratus |
| Non-Echinoderm Reactivity | |
| Description: | Species-specific antibody demonstrated to inhibit sperm binding and subsequent fertilization by reacting with a plasma membrane receptor within purple sea urchin eggs. Created by K. R. Foltz and W. J. Lennarz (State University of New York at Stony Brook). |
| Immunogen | |
| Name | 70-kD LysC Fragment |
| Type | polypeptide |
| Post Translational Modifications | Glycosylation |
| Source Organism | purple sea urchin |
| Description | Extracellular glycoprotein region prepared using DEAE-chromatography on crude egg proteins digested using lysylendoproteinase C. |
| Sequence | |
| Reported Usage | |
| immunofluorescence | |
| immunoprecipitation | |
| western blot | |
| immunohistochemistry | |
| Publications | |
| First: |
Identification of the sea urchin egg receptor for sperm using an antiserum raised against a fragment of its extracellular domain., J Cell Biol 1992 |
| Most recent: |
Surface localization of the sea urchin egg receptor for sperm., Dev Biol 1997 |
| View All Papers | |