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ECB-ANTIBODY-26396026
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Antibody Name:
tubb1 Ab4
Common Name: polyglutamylated tubulin alpha-1A chain RRID: Synonyms: B3, polyglutamylated alpha-tubulin
Source: |
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| Antibody | |
| Clone Number | B3 |
| Purification | Immunoglobulin Fractionation |
| Isotype | IgM |
| Host Organism | mouse |
| Echinoderm Reactivity | S. purpuratus, P. lividus, L. pictus |
| Non-Echinoderm Reactivity | |
| Description: | Antibody that specifically recognizes a polyglutamylated motif on the C-terminal end of alpha-tubulin that was demonstrated to inhibit sea urchin sperm mobility in vitro. Created and screened from a panel of monoclonal antibodies by Gagnon et al. (Urology Research Laboratory, Royal Victoria Hospital, McGill University, Montreal, Canada). Also reacts with dinoflagellates (Oxyrrhis marina). |
| Immunogen | |
| Name | Sea Urchin Sperm Axonemes |
| Type | polypeptide |
| Post Translational Modifications | unknown post translational modifications |
| Source Organism | Lytechinus pictus |
| Description | Fractions purified from sea urchin spermatozoa containing a polyglutamylated (Glu445) form of alpha-tubulin |
| Sequence |
[+]
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| Reported Usage | |
| enzyme-linked immunosorbent assay | |
| immunofluorescence | |
| immunohistochemistry | |
| western blot | |
| Publications | |
| ???displayAntibody.papersFirst??? |
The polyglutamylated lateral chain of alpha-tubulin plays a key role in flagellar motility., J Cell Sci 1996 |
| ???displayAntibody.papersRecent??? |
Differential distribution of glutamylated tubulin isoforms along the sea urchin sperm axoneme., Mol Reprod Dev 2002 |
| ???displayAntibody.papersAll??? | |