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Antibody Name: LOC373247 Ab2 Common Name: nuclear intermediate filament protein RRID: Synonyms: B-type nuclear lamin, IFA, TIB-131, neurofilament Antigens Gene: LOC373247 Clone Type: Monoclonal Source:

Antibody
Clone Number	TIB-131
Purification	obsolete cell fraction
Isotype	IgG1
Host Organism	mouse
Echinoderm Reactivity	S. purpuratus, L. pictus
Non-Echinoderm Reactivity	human, rat, worm
Description:	Reacts with the epitope, YRKLLEGEE, a highly conserved amino acid sequence present in intermediate filament proteins in invertebrates and vertebrates. Originally created and previously supplied by Rebecca M. Pruss (University College London) and Brian H. Anderton (St. George's Hospital Medical School) (PMID: 6086105). Currently supplied by ATCC (American Type Culture Collection). Also confirmed to react with Strongylocentrotus droebachiensis and Cucumaria frondosa.
Immunogen
Name	Glial Fibrillary Acidic Protein (GFAP)
Type	polypeptide
Post Translational Modifications	None
Source Organism	human
Description	Full-length native ~50 kD protein prepared from postmortem spinal cord tissue. Uniprot ID #: P14136.
Sequence
Reported Usage
western blot
immunofluorescence
Publications
???displayAntibody.papersFirst???	Studies of tektin filaments from flagellar microtubules by immunoelectron microscopy., J Cell Sci Suppl 1986
???displayAntibody.papersRecent???	Intermediate filament proteins in echinoderm coelomocytes., Comp Biochem Physiol B Biochem Mol Biol 2000
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