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Echinobase

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ECB-ANTIBODY-26395564

Antibody Name: LOC373178 Ab6

Common Name: kinesin heavy chain

RRID:
Synonyms: SUK6, kinesin family member 5B

Antigens
Gene: LOC373178

Clone Type: Monoclonal
Source:

Antibody
Clone Number SUK6
Purification Immunoglobulin Fractionation
Isotype IgG1
Host Organism mouse
Echinoderm Reactivity S. purpuratus
Non-Echinoderm Reactivity cow
Description: Function-blocking antibody that cross-reacts with a 120-kD protein in bovine brain and has been demonstrated to inhibit kinesin-mediated microtubule motility in vitro by binding to a ATP-sensitive motor domain. Created and screened from a panel of monoclonal antibodies by Amie L. Ingold, Stanley A. Cohn, and Jonathan M. Scholey at the University of Colorado Health Science Center.
Immunogen
Name ATP/EDTA Recycled Kinesin
Type polypeptide
Post Translational Modifications None
Source Organism purple sea urchin
Description Native 130-kD protein affinity-purified from microtubules extracted from sea urchin eggs.
Sequence
Reported Usage
western blot
enzyme-linked immunosorbent assay
Publications
???displayAntibody.papersFirst??? Inhibition of kinesin-driven microtubule motility by monoclonal antibodies to kinesin heavy chains., J Cell Biol 1988  
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