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Antibody Name: tpc2 Ab1 Common Name: two-pore calcium channel 2 RRID: Synonyms: TPC2 Antigens Gene: tpc2 Clone Type: Polyclonal Source:

Antibody
Clone Number
Purification	Affinity Purification
Isotype	isotype unknown
Host Organism	rabbit
Echinoderm Reactivity	S. purpuratus
Non-Echinoderm Reactivity
Description:	Isoform-specific antibody commercially generated at Covalab or Eurogentec then affinity-purified in the Galione lab at the Department of Pharmacology at the University of Oxford in the United Kingdom.
Immunogen
Name	Peptide a and peptide b
Type	synthetic sequence
Post Translational Modifications	None
Source Organism	purple sea urchin
Description	Two different peptides conjugated to BSA injected simultaneously.
Sequence	[+] QKQPIHRKVYPIYGC, CDEIYKHPHIQNLRF
Reported Usage
immunofluorescence
immunoprecipitation
western blot
Publications
???displayAntibody.papersFirst???	Purified TPC isoforms form NAADP receptors with distinct roles for Ca(2+) signaling and endolysosomal trafficking., Curr Biol 2010
???displayAntibody.papersRecent???	Photoaffinity labeling of high affinity nicotinic acid adenine dinucleotide phosphate (NAADP)-binding proteins in sea urchin egg., J Biol Chem 2012
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