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ECB-ANTIBODY-26395171

Antibody Name: FSCN1 Ab1

Common Name: fascin

RRID:
Synonyms: Sp-Fascin1, Sp-Fscn1, actin bundling protein, singed

Antigens
Gene: FSCN1

Clone Type: Polyclonal
Source:

Antibody
Clone Number
Purification
Isotype IgG
Host Organism rabbit
Echinoderm Reactivity S. purpuratus
Non-Echinoderm Reactivity
Description: Stains striated actin cross-linking protein bundles in filopodia in coelomocytes and microvillae in fertilized eggs. Demonstrated to react with Tripneustes gratilla, Strongylocentrotus purpuratus, Dendraster excentricus, and Strongylocentrotus droebachiensis. Antibody created by Dr. Joann Otto, Robert E. Kane, and Joseph Bryan at Friday Harbor Laboratories. Previously supplied by Dr. Joann Otto (Western Washington University).
Immunogen
Name sea urchin fascin
Type polypeptide
Post Translational Modifications None
Source Organism Echinoderms
Description 58 kDA protein band purified from Tripneustes gratilla egg extracts using SDS-polyacrylamide gel electrophoresis.
Sequence
Reported Usage
immunofluorescence
immunoprecipitation
western blot
Publications
First: Formation of filopodia in coelomocytes: localization of fascin, a 58,000 dalton actin cross-linking protein., Cell 1979  
Most recent: Structure and dynamics of an Arp2/3 complex-independent component of the lamellipodial actin network., Cell Motil Cytoskeleton 2009  
View All Papers