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Echinobase

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ECB-ANTIBODY-26395133

Antibody Name: LOC578390 Ab1

Common Name: microtubule-associated proteins 1A/1B light chain 3A

RRID:
Synonyms: 1B_Lc3L1, MAP1A/1B light chain 3, MAP1A/MAP1B LC3, Microtubule-associated proteins 1A/1B light chain 3B precursor, Sp-Map1a/1B_Lc3L1

Antigens
Gene: LOC578390

Clone Type: Polyclonal
Source: Sigma-Aldrich

Antibody
Clone Number
Purification Affinity Purification
Isotype isotype unknown
Host Organism rabbit
Echinoderm Reactivity Echinoderm
Non-Echinoderm Reactivity human, mouse, rat
Description: Recognizes active isoform (LC3-II) that serves as a marker for autophagosomes. Tested on Paracentrotus lividus and Strongylocentrotus intermedius.
Immunogen
Name
Type synthetic sequence
Post Translational Modifications None
Source Organism human
Description Corresponds to amino acids of human LC3A isoform a, conjugated to KLH via C-terminal cysteine residue. Identical in rat and mouse.
Sequence
Reported Usage
immunofluorescence
immunohistochemistry
western blot
Publications
???displayAntibody.papersFirst??? Sea urchin embryos as a model system for studying autophagy induced by cadmium stress., Autophagy 2011  
???displayAntibody.papersRecent??? Macroautophagy is involved in residual bodies formation during spermatogenesis in sea urchins, Strongylocentrotus intermedius., Tissue Cell 2019  
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