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J Food Sci Technol
2022 Jan 01;591:239-248. doi: 10.1007/s13197-021-05007-6.
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Antioxidant and antibacterial activities in 21 species of Indonesian sea cucumbers.
Nugroho A
,
Harahap IA
,
Ardiansyah A
,
Bayu A
,
Rasyid A
,
Murniasih T
,
Setyastuti A
,
Putra MY
.
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Sea cucumbers are marine organisms with uses in food, cosmetics, and medicine. This study aimed to identify Indonesian sea cucumbers with high antioxidant and antibacterial activities. Twenty-one sea cucumber species were used for this study. Antioxidant capacity was evaluated using the 2,2-diphenyl-β-picrylhydrazine assay. Antibacterial activity was assessed using the disk diffusion assay, whereas the resazurin-based assay was employed to determine the minimum inhibitory concentration (MIC) and minimum bactericidal concentration (MBC). Volatile compounds possibly related to the biological activity of sea cucumbers were analyzed via gas chromatography-mass spectrometry (GC-MS). Holothuria atra had the strongest antioxidant capacity (IC50 = 14.22 ± 0.87 µg µL-1). Stichopus vastus displayed the best antibacterial activity against Staphylococcus aureus, whereas Stichopus ocellatus extract was most potent against Vibrio cholerae. Holothuria albiventer, which controlled Bacillus subtilis most effectively while also being active against S. aureus and V. cholerae, was the optimal antimicrobial species. H. albiventer and Actinopyga echinites inhibited B. subtilis growth at 12.5 µg µL-1. The MBC tests indicated that the antibacterial activities of sea cucumbers at the MIC were bacteriostatic, rather than bactericidal, in nature. GC-MS analysis uncovered long-chain fatty acids that might be associated with the antibacterial activities of sea cucumbers.
Adibpour,
Antibacterial and Antifungal Activity of Holothuria leucospilota Isolated From Persian Gulf and Oman Sea.
2014, Pubmed,
Echinobase
Adibpour,
Antibacterial and Antifungal Activity of Holothuria leucospilota Isolated From Persian Gulf and Oman Sea.
2014,
Pubmed
,
Echinobase
Ak,
Antioxidant and radical scavenging properties of curcumin.
2008,
Pubmed
Andrews,
Determination of minimum inhibitory concentrations.
2001,
Pubmed
Bordbar,
High-value components and bioactives from sea cucumbers for functional foods--a review.
2011,
Pubmed
,
Echinobase
Dhinakaran,
Bioactive compounds from Holothuria atra of Indian ocean.
2014,
Pubmed
,
Echinobase
Elshikh,
Resazurin-based 96-well plate microdilution method for the determination of minimum inhibitory concentration of biosurfactants.
2016,
Pubmed
Esmat,
Bioactive compounds, antioxidant potential, and hepatoprotective activity of sea cucumber (Holothuria atra) against thioacetamide intoxication in rats.
2013,
Pubmed
,
Echinobase
Freire-Moran,
Critical shortage of new antibiotics in development against multidrug-resistant bacteria-Time to react is now.
2011,
Pubmed
Gülçin,
Antioxidant activity of caffeic acid (3,4-dihydroxycinnamic acid).
2006,
Pubmed
Gülçin,
Antioxidant activity of food constituents: an overview.
2012,
Pubmed
Jorgensen,
Antimicrobial susceptibility testing: a review of general principles and contemporary practices.
2009,
Pubmed
Mujeeb,
Phytochemical evaluation, antimicrobial activity, and determination of bioactive components from leaves of Aegle marmelos.
2014,
Pubmed
Nemeth,
Bacteriostatic versus bactericidal antibiotics for patients with serious bacterial infections: systematic review and meta-analysis.
2015,
Pubmed
Pangestuti,
Medicinal and health benefit effects of functional sea cucumbers.
2018,
Pubmed
,
Echinobase
Radjasa,
Characterization of psychrotrophic bacteria in the surface and deep-sea waters from the northwestern Pacific Ocean based on 16S ribosomal DNA analysis.
2001,
Pubmed
Sarker,
Microtitre plate-based antibacterial assay incorporating resazurin as an indicator of cell growth, and its application in the in vitro antibacterial screening of phytochemicals.
2007,
Pubmed
Spížek,
Do we need new antibiotics? The search for new targets and new compounds.
2010,
Pubmed
Sánchez,
Antimycobacterial susceptibility testing methods for natural products research.
2010,
Pubmed
Tuem,
Drug Resistance Patterns of Escherichia coli in Ethiopia: A Meta-Analysis.
2018,
Pubmed
Yoon,
Antibacterial Free Fatty Acids and Monoglycerides: Biological Activities, Experimental Testing, and Therapeutic Applications.
2018,
Pubmed
Zheng,
Fatty acid synthesis is a target for antibacterial activity of unsaturated fatty acids.
2005,
Pubmed
