Hossain A et al. (2020), Northern Sea Cucumber (Cucumaria frondosa): A P...

ECB-ART-49813

Mar Drugs 2020 May 22;185:. doi: 10.3390/md18050274.

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Northern Sea Cucumber (Cucumaria frondosa): A Potential Candidate for Functional Food, Nutraceutical, and Pharmaceutical Sector.

Hossain A , Dave D , Shahidi F .

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Sea cucumber (Cucumaria frondosa) is the most abundant and widely distributed species in the cold waters of North Atlantic Ocean. C. frondosa contains a wide range of bioactive compounds, mainly collagen, cerebrosides, glycosaminoglycan, chondroitin sulfate, saponins, phenols, and mucopolysaccharides, which demonstrate unique biological and pharmacological properties. In particular, the body wall of this marine invertebrate is the major edible part and contains most of the active constituents, mainly polysaccharides and collagen, which exhibit numerous biological activities, including anticancer, anti-hypertensive, anti-angiogenic, anti-inflammatory, antidiabetic, anti-coagulation, antimicrobial, antioxidation, and anti- osteoclastogenic properties. In particular, triterpene glycosides (frondoside A and other) are the most researched group of compounds due to their potential anticancer activity. This review summarizes the latest information on C. frondosa, mainly geographical distribution, landings specific to Canadian coastlines, processing, commercial products, trade market, bioactive compounds, and potential health benefits in the context of functional foods and nutraceuticals.

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References [+] :

Adrian, Novel marine-derived anti-cancer agents. 2007, Pubmed

	Figure 1. Body parts of Cucumaria frondosa.
	Figure 2. Distribution of the Northern sea cucumber (Cucumaria frondosa).
	Figure 3. Volume of Atlantic and Pacific Coasts commercial landings (metric tons, live weight).
	Figure 4. Value of Atlantic and Pacific Coasts commercial landings (thousand dollars, C$).
	Figure 5. Butterfly cut (dried with meat) and cocoon cut (dried with meat).
	Figure 6. Most common C. frondosa products in the market.
	Figure 7. Bioactive compounds of C. frondosa and their potential health benefit.
	Figure 8. Structure of repeating disaccharide units in chondroitin sulfate.
	Figure 9. Primary amino acid sequence of type I collagen.
	Figure 10. Chemical structures of different frondosides [82].