ECB-ART-41039
Planta Med
2009 May 01;756:647-53. doi: 10.1055/s-0029-1185381.
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Antifungal triterpene glycosides from the sea cucumber Holothuria (Microthele) axiloga.
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Three new holostan-type triterpene glycosides, arguside F (1), impatienside B (2), and pervicoside D (3), together with a known saponin, holothurin B ( 4) were isolated from the sea cucumber Holothuria (Microthele) axiloga H. L. Clark. On the basis of spectroscopic data and chemical reactions, the structures of the new compounds were elucidated. Compound 2 showed significant antifungal activities against six strains (1 < or = MIC(80) < or = 4 microg/mL). The stereochemistry of holothurin B (4) isolated from the title sea cucumber was also solved through X-ray diffraction analysis.
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Genes referenced: LOC100887844