Adv Space Biol Med 2003 Jan 01;9:83-99. doi: 10.1016/s1569-2574(03)09004-x.

Morphogenesis and gravity in a whole amphibian embryo and in isolated blastomeres of sea urchins.

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Fertilization and subsequent embryogenesis of newts occurred normally under microgravity in two Astronewt flight experiments. By accumulation of the results from the amphibian flight experiments including ''Astronewt'', it is considered that gravity has rather small effects on the early development of amphibian eggs. However, some temporary abnormalities, which recover in the course of the further developmental process, have been observed. Some regulations may occur in whole embryos. For a thorough knowledge about the role of gravity in morphogenesis, we need to investigate the gravitational effects on a single cell in a whole embryo. We propose a new experimental system with sea urchin embryos and micromeres for further studies at a cellular level of the effects of gravity on morphogenesis.

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Genes referenced: LOC100887844 LOC115919910