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Echinobase
ECB-ART-36282
Dev Comp Immunol 1995 Jan 01;193:217-24. doi: 10.1016/0145-305x(95)00009-i.
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Lipopolysaccharide activates the sea urchin immune system.

Smith LC , Britten RJ , Davidson EH .


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Profilin is a small, actin-binding protein that functions at the intersection of signal transduction and cytoskeletal modifications. Increases in the number of profilin messages per cell correlate with sea urchin coelomocytes activation in response to injury. Here we show that coelomocytes respond to immune challenge from lipopolysaccharide with significant elevations in profilin transcripts per coelomyocyte.

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Genes referenced: coel1 LOC100887844 LOC115919910 LOC590297