Echinobase will be undergoing a hardware update June 13 and 14, 2023 and therefore will be unavailable those days.

We apologize for the inconvenience.

Click on this message to dismiss it.
Click here to close Hello! We notice that you are using Internet Explorer, which is not supported by Echinobase and may cause the site to display incorrectly. We suggest using a current version of Chrome, FireFox, or Safari.
J Cell Biol 1972 May 01;532:419-34. doi: 10.1083/jcb.53.2.419.
Show Gene links Show Anatomy links

The contractile ring. II. Determining its brief existence, volumetric changes, and vital role in cleaving Arbacia eggs.

Schroeder TE .

The first cleavage furrow in eggs of Arbacia (sea urchin) is accompanied by a uniform ring of aligned microfilaments, called the contractile ring. Individual contractile ring filaments measure 35-60 A and occasionally appear "hollow." The contractile ring exists from about 20 sec after anaphase to the end of furrowing activity, i.e., 6-7 min at 20 degrees C. It is closely associated with the plasma membrane at all times, and is probably assembled there. It is about 8 micro wide and 0.2 micro thick throughout cleavage. Its volume decreases, however, suggesting a contraction-related disassembly of contractile ring filaments, rather than a sliding-filament mechanism in the strict sense. Cytochalasin B (>10(-6)M) arrests cleavage within 60 sec, by which time contractile ring filaments are no longer visible ultrastructurally. The furrow may be seen to recede within this time. Karyokinesis is unaffected. Simultaneous disruption of furrowing activity and of the contractile ring largely confirms the vital role of the contractile ring as the organelle of cell cleavage.

PubMed ID: 5063470
PMC ID: PMC2108733
Article link: J Cell Biol

Genes referenced: LOC100887844 LOC115919910

References [+] :
Anderson, Oocyte differentiation in the sea urchin, Arbacia punctulata, with particular reference to the origin of cortical granules and their participation in the cortical reaction. 1968, Pubmed, Echinobase