Cell Biol Int Rep 1988 Oct 01;1210:857-66. doi: 10.1016/0309-1651(88)90049-5.

Induction of the cortical reaction in isolated sea urchin egg cortices: effects of Ca2+ and ionophore A23187.

???displayArticle.abstract???
The cortical reaction in isolated sea urchin (Strongylocentrotus purpuratus) egg cortices has been monitored with phase-contrast video microscopy. It was confirmed that the cortical reaction is induced by exposure to Ca2+. No induction was observed after exposure to the Ca2+-ionophore A23187, although the cortices remain sensitive to a subsequent exposure to Ca2+, and the cortical reaction in unfertilized eggs suspended in cortex isolation medium remains inducible by exposure to A23187. These results imply: (1) that A23187 does not induce the cortical reaction directly; (2) that the release of intracellular Ca2+, through which A23187 induces the cortical reaction, is not from storage sites localized entirely in the cortex; and (3) that intracellular storage sites for the Ca2+ involved in the cortical reaction are also present outside the cortex.

???displayArticle.pubmedLink??? 3147143
???displayArticle.link??? Cell Biol Int Rep
???displayArticle.grants??? [+]

Genes referenced: LOC100887844