Click
here to close Hello! We notice that
you are using Internet Explorer, which is not supported by Echinobase
and may cause the site to display incorrectly. We suggest using a
current version of Chrome,
FireFox,
or Safari.
Nucleic Acids Res
1991 Mar 11;195:1093-8. doi: 10.1093/nar/19.5.1093.
Show Gene links
Show Anatomy links
The U1 snRNA gene repeat from the sea urchin (Strongylocentrotus purpuratus): the 70 kilobase tandem repeat ends directly 3'' to a U1 gene.
Yu JC
,
Wendelburg B
,
Sakallah S
,
Marzluff WF
.
???displayArticle.abstract???
Lambda phage clones containing multiple copies of the 1.1 kb tandemly repeated unit of the sea urchin (S. purpuratus) U1 RNA genes were isolated from a gene library. The 1.1 kb repeat unit encodes a single copy of the predominant U1 RNA expressed in oocytes and embryos prior to the blastula stage. The tandem repeat unit is about 80 kb in size and is probably present one time per haploid genome as judged by pulsed-field electrophoresis of sperm DNA digested with restriction enzymes which do not cut in the repeat unit. Two of the phage contained DNA flanking the repeat unit as well as several repeat units. The tandem repeat unit ends just 3'' to the U1 coding region. There is only limited homology in the 5'' flanking region with U1 snRNA genes from the sea urchin L. variegatus.
Ach,
The highly conserved U small nuclear RNA 3'-end formation signal is quite tolerant to mutation.
1987, Pubmed
Ach,
The highly conserved U small nuclear RNA 3'-end formation signal is quite tolerant to mutation.
1987,
Pubmed
Ares,
Orientation-dependent transcriptional activator upstream of a human U2 snRNA gene.
1985,
Pubmed
Birnstiel,
Transcription termination and 3' processing: the end is in site!
1985,
Pubmed
Brown,
How a simple animal gene works.
1982,
Pubmed
Brown,
Structure of the sea urchin U1 RNA repeat.
1985,
Pubmed
,
Echinobase
Card,
Sea urchin small nuclear RNA genes are organized in distinct tandemly repeating units.
1982,
Pubmed
,
Echinobase
De Lorenzi,
Analysis of a sea urchin gene cluster coding for the small nuclear U7 RNA, a rare RNA species implicated in the 3' editing of histone precursor mRNAs.
1986,
Pubmed
,
Echinobase
Earley,
Three linked chicken U1 RNA genes have limited flanking DNA sequence homologies that reveal potential regulatory signals.
1984,
Pubmed
Gardiner,
Fractionation of large mammalian DNA restriction fragments using vertical pulsed-field gradient gel electrophoresis.
1986,
Pubmed
Hardin,
Structure of the Spec1 gene encoding a major calcium-binding protein in the embryonic ectoderm of the sea urchin, Strongylocentrotus purpuratus.
1985,
Pubmed
,
Echinobase
Hentschel,
The organization and expression of histone gene families.
1981,
Pubmed
Lund,
True genes for human U1 small nuclear RNA. Copy number, polymorphism, and methylation.
1984,
Pubmed
Lund,
The two embryonic U1 small nuclear RNAs of Xenopus laevis are encoded by a major family of tandemly repeated genes.
1984,
Pubmed
Lund,
Differential accumulation of U1 and U4 small nuclear RNAs during Xenopus development.
1987,
Pubmed
Maniatis,
The role of small nuclear ribonucleoprotein particles in pre-mRNA splicing.
1987,
Pubmed
Mattaj,
Changing the RNA polymerase specificity of U snRNA gene promoters.
1988,
Pubmed
Maxson,
Expression and organization of histone genes.
1983,
Pubmed
,
Echinobase
Murphy,
Functional elements of the human U1 RNA promoter. Identification of five separate regions required for efficient transcription and template competition.
1987,
Pubmed
Nash,
A developmental switch in sea urchin U1 RNA.
1989,
Pubmed
,
Echinobase
Nash,
Structure of an unusual sea urchin U1 RNA gene cluster.
1988,
Pubmed
,
Echinobase
Nijhawan,
Metabolism of low molecular weight ribonucleic acids in early sea urchin embryos.
1979,
Pubmed
,
Echinobase
Sanger,
DNA sequencing with chain-terminating inhibitors.
1977,
Pubmed
Santiago,
Expression of the U1 RNA gene repeat during early sea urchin development: evidence for a switch in U1 RNA genes during development.
1989,
Pubmed
,
Echinobase
Schwartz,
Separation of yeast chromosome-sized DNAs by pulsed field gradient gel electrophoresis.
1984,
Pubmed
Sharp,
Splicing of messenger RNA precursors.
1987,
Pubmed
Skuzeski,
Synthesis of human U1 RNA. II. Identification of two regions of the promoter essential for transcription initiation at position +1.
1984,
Pubmed
Strub,
Genetic complementation in the Xenopus oocyte: co-expression of sea urchin histone and U7 RNAs restores 3' processing of H3 pre-mRNA in the oocyte.
1986,
Pubmed
,
Echinobase
Yu,
Structure and expression of a second sea urchin U1 RNA gene repeat.
1986,
Pubmed
,
Echinobase
Zeller,
Xenopus laevis U1 snRNA genes: characterisation of transcriptionally active genes reveals major and minor repeated gene families.
1984,
Pubmed
