Gene Symbol :  nr2c2 Symbol Status : Provisional Gene Name:  nuclear receptor subfamily 2 group C member 2 Name Status : Provisional Synonyms: Sp-Shr2 , SPU_008117 , steroid hormone receptor 2 , SpSHR2 , nuclear receptor subfamily 2 group C-like , Nr2c-like [+] , LOC110989750 [-] ( Nomenclature history ) Gene Function: Orphan nuclear receptor. Binds to the hormone response element in the upstream promoter region of the CYIIIB gene in vitro. Both isoform 1 and isoform 2 bind DNA. Subcellular location: The subcellular location of isoform 1 alters throughout development. In the unfertilized egg, isoform 1 expression is cytoplasmic and concentrated around the pronucleus. Following fertilization, the cytoplasmic protein rapidly enters the embryonic nuclei where it appears as speckles. From the fourth cleavage stage onward Protein Function : InterPro : Nuclear hrmn rcpt , Znf NHR/GATA , Nucl hrmn rcpt lig-bd , Znf hrmn rcpt [+] , NHR-like dom sf [-] Interactants: Loading ... Diseases:  External Links: ClinVar, ClinGen, MalaCards, KEGG Disease, DECIPHER, COSMIC, MARRVEL, GTR, DisGeNET, dbVAR, GHR, gnomAD

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