ECB-GENEPAGE-23163627
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:
adam10
Symbol Status
:
Partially Curated
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:
ADAM metallopeptidase domain 10
Name Status
:
Partially Curated
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SPU_028174
,
Sp-Unk_18
(
Nomenclature history )
AI Protein Function
:
adam10 is a membrane‑bound metalloprotease that acts as a sheddase for the Notch receptor, enabling Notch pathway activation during embryogenesis. It mediates proteolytic cleavage of cell‑adhesion mole...[+]
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Diseases:
Disease Ontology:
Alzheimer's disease 18
MIM:
ALZHEIMER DISEASE 18; AD18
External Links:
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Symbol legend: