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Echinobase

Summary ExpressionExpr. Gene Literature (13)Lit. (13) GO Terms (28)GO (28) Nucleotides (12)Nucl. (12) Proteins (9)Prot. (9) Interactants (110)Interact. (110) Wiki
ECB-GENEPAGE-23158311
???displayGene.symbol??? :
 apc
Symbol Status : Curated


???displayGene.name???: 
APC regulator of WNT signaling pathway
Name Status : Curated


???displayGene.synonyms???
adenomatous polyposis coli protein , LOC110987304 , LOC578083 , p120 , Sp-Apc , Sp-P120L [+] ( Nomenclature history )

AI Protein Function :
apc encodes a scaffolding protein that participates in the β‑catenin destruction complex, acting as a negative regulator of canonical Wnt signaling; it binds microtubules and modulates cytoskeletal dyn...[+]


???displayGene.geneInteractants???
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Diseases: 


Disease Ontology:
familial adenomatous polyposis [+]

MIM:
FAMILIAL ADENOMATOUS POLYPOSIS 1; FAP1 [+]

External Links:
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