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Summary Expression Gene Literature (64) GO Terms (4) Nucleotides (3) Proteins (3) Interactants (94) Wiki
ECB--23025863

Papers associated with LOC574780



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Frondoside A Enhances the Anti-Cancer Effects of Oxaliplatin and 5-Fluorouracil on Colon Cancer Cells., Attoub S, Arafat K, Khalaf T, Sulaiman S, Iratni R., Nutrients. 10 (5):   


Polysaccharide enhanced NK cell cytotoxicity against pancreatic cancer via TLR4/MAPKs/NF-κB pathway in vitro/vivo., Xie X, Ma L, Zhou Y, Shen W, Xu D, Dou J, Shen B, Zhou C., Carbohydr Polym. December 1, 2019; 225 115223.

Structural Features and Digestive Behavior of Fucosylated Chondroitin Sulfate from Sea Cucumbers Stichopus japonicus., Zhu Z, Dong X, Yan C, Ai C, Zhou D, Yang J, Zhang H, Liu X, Song S, Xiao H, Zhu B., J Agric Food Chem. September 18, 2019; 67 (37): 10534-10542.

Looking at Marine-Derived Bioactive Molecules as Upcoming Anti-Diabetic Agents: A Special Emphasis on PTP1B Inhibitors., Ezzat SM, Bishbishy MHE, Habtemariam S, Salehi B, Sharifi-Rad M, Martins N, Sharifi-Rad J., Molecules. December 15, 2018; 23 (12):   

Digestibility of fucosylated glycosaminoglycan from sea cucumber and its effects on digestive enzymes under simulated salivary and gastrointestinal conditions., Zhao L, Qin Y, Guan R, Zheng W, Liu J, Zhao J., Carbohydr Polym. April 15, 2018; 186 217-225.

New Neuronal Subtypes With a "Pre-Pancreatic" Signature in the Sea Urchin Stongylocentrotus purpuratus., Perillo M, Paganos P, Mattiello T, Cocurullo M, Oliveri P, Arnone MI., Front Endocrinol (Lausanne). January 1, 2018; 9 650.   


Macromolecular properties and hypolipidemic effects of four sulfated polysaccharides from sea cucumbers., Li S, Li J, Zhi Z, Wei C, Wang W, Ding T, Ye X, Hu Y, Linhardt RJ, Chen S., Carbohydr Polym. October 1, 2017; 173 330-337.

Frondoside A from sea cucumber and nymphaeols from Okinawa propolis: Natural anti-cancer agents that selectively inhibit PAK1 in vitro., Nguyen BCQ, Yoshimura K, Kumazawa S, Tawata S, Maruta H., Drug Discov Ther. May 30, 2017; 11 (2): 110-114.

Anti-diabetic activity of Holothuria thomasi saponin., El Barky AR, Hussein SA, Alm-Eldeen AA, Hafez YA, Mohamed TM., Biomed Pharmacother. December 1, 2016; 84 1472-1487.

Saponin-enriched sea cucumber extracts exhibit an antiobesity effect through inhibition of pancreatic lipase activity and upregulation of LXR-β signaling., Guo L, Gao Z, Zhang L, Guo F, Chen Y, Li Y, Huang C., Pharm Biol. August 1, 2016; 54 (8): 1312-25.

Pharmacokinetics in Mouse and Comparative Effects of Frondosides in Pancreatic Cancer., Al Shemaili J, Parekh KA, Newman RA, Hellman B, Woodward C, Adem A, Collin P, Adrian TE., Mar Drugs. June 17, 2016; 14 (6):   


A pancreatic exocrine-like cell regulatory circuit operating in the upper stomach of the sea urchin Strongylocentrotus purpuratus larva., Perillo M, Wang YJ, Leach SD, Arnone MI., BMC Evol Biol. May 26, 2016; 16 (1): 117.   


Mechanisms of echinochrome potency in modulating diabetic complications in liver., Mohamed AS, Soliman AM, Marie MAS., Life Sci. April 15, 2016; 151 41-49.

Fucoidan from Acaudina molpadioides protects pancreatic islet against cell apoptosis via inhibition of inflammation in type 2 diabetic mice., Wang J, Wang J, Hu S, Wang J, Wang J, Li S, Jiang W., Food Sci Biotechnol. February 29, 2016; 25 (1): 293-300.

Measurement of luminal pH of acidic stores as a readout for NAADP action., Galione A, Chuang KT, Funnell TM, Davis LC, Morgan AJ, Ruas M, Parrington J, Churchill GC., Cold Spring Harb Protoc. October 1, 2014; 2014 (10): pdb.prot076935.

The Evolution and Variety of RFamide-Type Neuropeptides: Insights from Deuterostomian Invertebrates., Elphick MR, Mirabeau O., Front Endocrinol (Lausanne). May 13, 2014; 5 93.   


Frondoside A enhances the antiproliferative effects of gemcitabine in pancreatic cancer., Al Shemaili J, Mensah-Brown E, Parekh K, Thomas SA, Attoub S, Hellman B, Nyberg F, Adem A, Collin P, Adrian TE., Eur J Cancer. May 1, 2014; 50 (7): 1391-8.

Effects of two sulfated triterpene saponins echinoside A and holothurin A on the inhibition of dietary fat absorption and obesity reduction., Wang Y, Wang J, Wang J, Yanagita RC, Liu C, Hu X, Dong P, Xue C, Xue Y., Biosci Biotechnol Biochem. January 1, 2014; 78 (1): 139-46.

RNA-Seq reveals dynamic changes of gene expression in key stages of intestine regeneration in the sea cucumber Apostichopus japonicus. [corrected]., Sun L, Yang H, Chen M, Ma D, Lin C., PLoS One. January 1, 2013; 8 (8): e69441.   


Photoaffinity labeling of nicotinic acid adenine dinucleotide phosphate (NAADP) targets in mammalian cells., Lin-Moshier Y, Walseth TF, Churamani D, Davidson SM, Slama JT, Hooper R, Brailoiu E, Patel S, Marchant JS., J Biol Chem. January 20, 2012; 287 (4): 2296-307.

Effects of bioactive components of sea cucumber on the serum, liver lipid profile and lipid absorption., Hu XQ, Xu J, Xue Y, Li ZJ, Wang JF, Wang JF, Wang JH, Wang JH, Xue CH, Wang YM., Biosci Biotechnol Biochem. January 1, 2012; 76 (12): 2214-8.

Frondoside A inhibits human breast cancer cell survival, migration, invasion and the growth of breast tumor xenografts., Al Marzouqi N, Iratni R, Nemmar A, Arafat K, Ahmed Al Sultan M, Yasin J, Collin P, Mester J, Adrian TE, Attoub S., Eur J Pharmacol. October 1, 2011; 668 (1-2): 25-34.

Anti-pancreatic cancer effects of a polar extract from the edible sea cucumber, Cucumaria frondosa., Roginsky AB, Ding XZ, Woodward C, Ujiki MB, Singh B, Bell RH, Collin P, Adrian TE., Pancreas. July 1, 2010; 39 (5): 646-52.

Purified TPC isoforms form NAADP receptors with distinct roles for Ca(2+) signaling and endolysosomal trafficking., Ruas M, Rietdorf K, Arredouani A, Davis LC, Lloyd-Evans E, Koegel H, Funnell TM, Morgan AJ, Ward JA, Watanabe K, Cheng X, Churchill GC, Zhu MX, Platt FM, Wessel GM, Parrington J, Galione A., Curr Biol. March 27, 2010; 20 (8): 703-9.   


Identification of a chemical probe for NAADP by virtual screening., Naylor E, Arredouani A, Vasudevan SR, Lewis AM, Parkesh R, Mizote A, Rosen D, Thomas JM, Izumi M, Ganesan A, Galione A, Churchill GC., Nat Chem Biol. April 1, 2009; 5 (4): 220-6.   


Review of the apoptosis pathways in pancreatic cancer and the anti-apoptotic effects of the novel sea cucumber compound, Frondoside A., Li X, Roginsky AB, Ding XZ, Woodward C, Collin P, Newman RA, Bell RH, Adrian TE., Ann N Y Acad Sci. September 1, 2008; 1138 181-98.

Refinement of a radioreceptor binding assay for nicotinic acid adenine dinucleotide phosphate., Lewis AM, Masgrau R, Vasudevan SR, Yamasaki M, O'Neill JS, Garnham C, James K, Macdonald A, Ziegler M, Galione A, Churchill GC., Anal Biochem. December 1, 2007; 371 (1): 26-36.   


Molecular characterization of a novel intracellular ADP-ribosyl cyclase., Churamani D, Boulware MJ, Geach TJ, Martin AC, Moy GW, Su YH, Vacquier VD, Marchant JS, Dale L, Patel S., PLoS One. August 29, 2007; 2 (8): e797.   


Cell-permeant small-molecule modulators of NAADP-mediated Ca2+ release., Dowden J, Berridge G, Moreau C, Yamasaki M, Churchill GC, Potter BV, Galione A., Chem Biol. June 1, 2006; 13 (6): 659-65.

Molecular cloning of two toxic phospholipases A2 from the crown-of-thorns starfish Acanthaster planci venom., Ota E, Nagai H, Nagashima Y, Shiomi K., Comp Biochem Physiol B Biochem Mol Biol. January 1, 2006; 143 (1): 54-60.

Human mesotrypsin defies natural trypsin inhibitors: from passive resistance to active destruction., Sahin-Tóth M., Protein Pept Lett. July 1, 2005; 12 (5): 457-64.

Role of NAADP and cADPR in the induction and maintenance of agonist-evoked Ca2+ spiking in mouse pancreatic acinar cells., Yamasaki M, Thomas JM, Churchill GC, Garnham C, Lewis AM, Cancela JM, Patel S, Galione A., Curr Biol. May 10, 2005; 15 (9): 874-8.

Purification of a fibrinolytic enzyme (myulchikinase) from pickled anchovy and its cytotoxicity to the tumor cell lines., Jeong YK, Yang WS, Kim KH, Chung KT, Joo WH, Kim JH, Kim DE, Park JU., Biotechnol Lett. March 1, 2004; 26 (5): 393-7.

Protection from pancreatitis by the zymogen granule membrane protein integral membrane-associated protein-1., Imamura T, Asada M, Vogt SK, Rudnick DA, Lowe ME, Muglia LJ., J Biol Chem. December 27, 2002; 277 (52): 50725-33.

Immunohistochemical validation of a novel epithelial and a novel stromal marker of pancreatic ductal adenocarcinoma identified by global expression microarrays: sea urchin fascin homolog and heat shock protein 47., Maitra A, Iacobuzio-Donahue C, Rahman A, Sohn TA, Argani P, Meyer R, Yeo CJ, Cameron JL, Goggins M, Kern SE, Ashfaq R, Hruban RH, Wilentz RE., Am J Clin Pathol. July 1, 2002; 118 (1): 52-9.

Nicotinic acid adenine dinucleotide phosphate: a new intracellular second messenger?, Chini EN, De Toledo FG., Am J Physiol Cell Physiol. June 1, 2002; 282 (6): C1191-8.

Isolation and characteristics of trypsin inhibitor from the hepatopancreas of a squid (Todarodes pacificus)., Kishimura H, Saeki H, Hayashi K., Comp Biochem Physiol B Biochem Mol Biol. August 1, 2001; 130 (1): 117-23.

Role of Ins(1,4,5)P3, cADP-ribose and nicotinic acid-adenine dinucleotide phosphate in Ca2+ signalling in mouse submandibular acinar cells., Harmer AR, Gallacher DV, Smith PM., Biochem J. February 1, 2001; 353 (Pt 3): 555-60.

Intracellular Ca(2+) release mechanisms: multiple pathways having multiple functions within the same cell type?, da Silva CP, Guse AH., Biochim Biophys Acta. December 20, 2000; 1498 (2-3): 122-33.

cDNA cloning and sequencing of phospholipase A2 from the pyloric ceca of the starfish Asterina pectinifera., Kishimura H, Ojima T, Hayashi K, Nishita K., Comp Biochem Physiol B Biochem Mol Biol. August 1, 2000; 126 (4): 579-86.

The pathogenesis of autosomal dominant polycystic kidney disease: an update., Somlo S, Markowitz GS., Curr Opin Nephrol Hypertens. July 1, 2000; 9 (4): 385-94.

NAADP-induced calcium release in sea urchin eggs., Galione A, Patel S, Churchill GC., Biol Cell. July 1, 2000; 92 (3-4): 197-204.

Nicotinic acid adenine dinucleotide phosphate-induced Ca(2+) release. Interactions among distinct Ca(2+) mobilizing mechanisms in starfish oocytes., Santella L, Kyozuka K, Genazzani AA, De Riso L, Carafoli E., J Biol Chem. March 24, 2000; 275 (12): 8301-6.

Cyclic ADP-ribose., Guse AH., J Mol Med (Berl). January 1, 2000; 78 (1): 26-35.

Nicotinic acid adenine dinucleotide phosphate triggers Ca2+ release from brain microsomes., Bak J, White P, Timár G, Missiaen L, Genazzani AA, Galione A., Curr Biol. July 15, 1999; 9 (14): 751-4.

Cyclic ADP-ribose: a novel Ca2+-mobilising second messenger., Guse AH., Cell Signal. May 1, 1999; 11 (5): 309-16.

Coordination of agonist-induced Ca2+-signalling patterns by NAADP in pancreatic acinar cells., Cancela JM, Churchill GC, Galione A., Nature. March 4, 1999; 398 (6722): 74-6.

The role of calcium on the activity of ERcalcistorin/protein-disulfide isomerase and the significance of the C-terminal and its calcium binding. A comparison with mammalian protein-disulfide isomerase., Lucero HA, Kaminer B., J Biol Chem. January 29, 1999; 274 (5): 3243-51.

Partial biochemical and immunologic characterization of fibrillin microfibrils from sea cucumber dermis., Thurmond FA, Koob TJ, Bowness JM, Trotter JA., Connect Tissue Res. January 1, 1997; 36 (3): 211-22.

Increased amounts of a high molecular weight insulin-like growth factor II (IGF-II) peptide and IGF-II messenger ribonucleic acid in pancreatic islets of diabetic Goto-Kakizaki rats., Höög A, Sandberg-Nordqvist AC, Abdel-Halim SM, Carlsson-Skwirut C, Guenifi A, Tally M, Ostenson CG, Falkmer S, Sara VR, Efendić S, Schalling M, Grimelius L., Endocrinology. June 1, 1996; 137 (6): 2415-23.

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