Dr. Isabelle Peter
PositionResearch Professor of Biology and Biological Engineering
The gene regulatory network controlling specification of endomesoderm in sea urchin embryos is one of the best understood experimentally solved gene regulatory networks. The ability of a computational Boolean model of this network to reconstruct the spatial and temporal expression of regulatory genes during early sea urchin development can be considered as a proof of principle that solving gene regulatory networks can indeed reveal the causality of developmental process. Using the endomesoderm network, we are now analyzing the role of individual regulatory linkages in the function of modular network circuits, and the functional organization of these circuits within the overall network.
Caltech - The Division of Biology and Biological Engineering
1200 E California Blvd
B184 Alles Laboratory