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Profile Publications(67)

Publications By Alberto Darszon

Results 1 - 50 of 67 results

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Crosstalk between protein kinases A and C regulates sea urchin sperm motility., Loza-Huerta A, Pacheco-Castillo H, Darszon A, Beltrán C., Zygote. June 1, 2022; 30 (3): 398-409.

CatSper channels in sea urchin sperm., Loyo-Celis V, Orta G, Beltrán C, Darszon A., Cell Calcium. November 1, 2021; 99 102466.

Sperm chemotaxis is driven by the slope of the chemoattractant concentration field., Ramírez-Gómez HV, Jimenez Sabinina V, Velázquez Pérez M, Beltran C, Carneiro J, Wood CD, Tuval I, Darszon A, Guerrero A., Elife. March 9, 2020; 9                                 

Modular analysis of the control of flagellar Ca2+-spike trains produced by CatSper and CaV channels in sea urchin sperm., Priego-Espinosa DA, Darszon A, Guerrero A, González-Cota AL, Nishigaki T, Martínez-Mekler G, Carneiro J., PLoS Comput Biol. March 2, 2020; 16 (3): e1007605.                    

Network model predicts that CatSper is the main Ca2+ channel in the regulation of sea urchin sperm motility., Espinal-Enríquez J, Priego-Espinosa DA, Darszon A, Beltrán C, Martínez-Mekler G., Sci Rep. June 26, 2017; 7 (1): 4236.                

Speract, a sea urchin egg peptide that regulates sperm motility, also stimulates sperm mitochondrial metabolism., García-Rincón J, Darszon A, Beltrán C., Biochim Biophys Acta. April 1, 2016; 1857 (4): 415-26.

Single cell imaging reveals that the motility regulator speract induces a flagellar alkalinization that precedes and is independent of Ca²⁺ influx in sea urchin spermatozoa., González-Cota AL, Silva PÂ, Carneiro J, Darszon A., FEBS Lett. July 22, 2015; 589 (16): 2146-54.

Soluble adenylyl cyclase of sea urchin spermatozoa., Vacquier VD, Loza-Huerta A, García-Rincón J, Darszon A, Beltrán C., Biochim Biophys Acta. December 1, 2014; 1842 (12 Pt B): 2621-8.

Zn(2+) induces hyperpolarization by activation of a K(+) channel and increases intracellular Ca(2+) and pH in sea urchin spermatozoa., Beltrán C, Rodríguez-Miranda E, Granados-González G, de De la Torre LG, Nishigaki T, Darszon A., Dev Biol. October 1, 2014; 394 (1): 15-23.

In silico determination of the effect of multi-target drugs on calcium dynamics signaling network underlying sea urchin spermatozoa motility., Espinal-Enríquez J, Darszon A, Guerrero A, Martínez-Mekler G., PLoS One. August 27, 2014; 9 (8): e104451.              

Intracellular pH in sperm physiology., Nishigaki T, José O, González-Cota AL, Romero F, Treviño CL, Darszon A., Biochem Biophys Res Commun. August 1, 2014; 450 (3): 1149-58.

Certain Strongylocentrotus purpuratus sperm mitochondrial proteins co-purify with low density detergent-insoluble membranes and are PKA or PKC-substrates possibly involved in sperm motility regulation., Loza-Huerta A, Vera-Estrella R, Darszon A, Beltrán C., Biochim Biophys Acta. November 1, 2013; 1830 (11): 5305-15.

Niflumic acid disrupts marine spermatozoan chemotaxis without impairing the spatiotemporal detection of chemoattractant gradients., Guerrero A, Espinal J, Wood CD, Rendón JM, Carneiro J, Martínez-Mekler G, Darszon A., J Cell Sci. March 15, 2013; 126 (Pt 6): 1477-87.

A segmentation algorithm for automated tracking of fast swimming unlabelled cells in three dimensions., Pimentel JA, Carneiro J, Darszon A, Corkidi G., J Microsc. January 1, 2012; 245 (1): 72-81.

Discrete dynamics model for the speract-activated Ca2+ signaling network relevant to sperm motility., Espinal J, Aldana M, Guerrero A, Wood C, Darszon A, Martínez-Mekler G., PLoS One. January 1, 2011; 6 (8): e22619.                  

Calmodulin antagonists inhibit sea urchin sperm hyperpolarization necessary for directed movement toward the egg., Galindo BE, Darszon A., Proc West Pharmacol Soc. January 1, 2011; 54 80-2.

Tuning sperm chemotaxis., Guerrero A, Wood CD, Nishigaki T, Carneiro J, Darszon A., Biochem Soc Trans. October 1, 2010; 38 (5): 1270-4.

Tuning sperm chemotaxis by calcium burst timing., Guerrero A, Nishigaki T, Carneiro J, Yoshiro Tatsu null, Wood CD, Darszon A., Dev Biol. August 1, 2010; 344 (1): 52-65.

Mitochondrial inhibitors activate influx of external Ca(2+) in sea urchin sperm., Ardón F, Rodríguez-Miranda E, Beltrán C, Hernández-Cruz A, Darszon A., Biochim Biophys Acta. January 1, 2009; 1787 (1): 15-24.

Tracking sperm in three-dimensions., Corkidi G, Taboada B, Wood CD, Guerrero A, Darszon A., Biochem Biophys Res Commun. August 15, 2008; 373 (1): 125-9.

Sperm-activating peptides in the regulation of ion fluxes, signal transduction and motility., Darszon A, Guerrero A, Galindo BE, Nishigaki T, Wood CD., Int J Dev Biol. January 1, 2008; 52 (5-6): 595-606.

Rho-kinase (ROCK) in sea urchin sperm: its role in regulating the intracellular pH during the acrosome reaction., de la Sancha CU, Martínez-Cadena G, López-Godínez J, Castellano LE, Nishigaki T, Nishisaki T, Darszon A, García-Soto J., Biochem Biophys Res Commun. December 21, 2007; 364 (3): 470-5.

Particulate and soluble adenylyl cyclases participate in the sperm acrosome reaction., Beltrán C, Vacquier VD, Moy G, Chen Y, Buck J, Levin LR, Darszon A., Biochem Biophys Res Commun. July 13, 2007; 358 (4): 1128-35.

Altering the speract-induced ion permeability changes that generate flagellar Ca2+ spikes regulates their kinetics and sea urchin sperm motility., Wood CD, Nishigaki T, Tatsu Y, Yumoto N, Baba SA, Whitaker M, Darszon A., Dev Biol. June 15, 2007; 306 (2): 525-37.

Sp-tetraKCNG: A novel cyclic nucleotide gated K(+) channel., Galindo BE, de la Vega-Beltrán JL, Labarca P, Vacquier VD, Darszon A., Biochem Biophys Res Commun. March 16, 2007; 354 (3): 668-75.

Rho, Rho-kinase, and the actin cytoskeleton regulate the Na+ -H+ exchanger in sea urchin eggs., Rangel-Mata F, Méndez-Márquez R, Martínez-Cadena G, López-Godínez J, Nishigaki T, Darszon A, García-Soto J., Biochem Biophys Res Commun. January 5, 2007; 352 (1): 264-9.

Ion channels in sperm motility and capacitation., Darszon A, Treviño CL, Wood C, Galindo B, Rodríguez-Miranda E, Acevedo JJ, Hernandez-González EO, Beltrán C, Martínez-López P, Nishigaki T., Soc Reprod Fertil Suppl. January 1, 2007; 65 229-44.

Sperm channel diversity and functional multiplicity., Darszon A, Acevedo JJ, Galindo BE, Hernández-González EO, Nishigaki T, Treviño CL, Wood C, Beltrán C., Reproduction. June 1, 2006; 131 (6): 977-88.

Identification of voltage-dependent Ca2+ channels in sea urchin sperm., Granados-Gonzalez G, Mendoza-Lujambio I, Rodriguez E, Galindo BE, Beltrán C, Darszon A., FEBS Lett. December 5, 2005; 579 (29): 6667-72.

A soluble adenylyl cyclase from sea urchin spermatozoa., Nomura M, Beltrán C, Darszon A, Vacquier VD., Gene. July 4, 2005; 353 (2): 231-8.

Real-time analysis of the role of Ca(2+) in flagellar movement and motility in single sea urchin sperm., Wood CD, Nishigaki T, Furuta T, Baba SA, Darszon A., J Cell Biol. June 6, 2005; 169 (5): 725-31.        

Sperm-activating peptide induces asymmetric flagellar bending in sea urchin sperm., Shiba K, Ohmuro J, Mogami Y, Nishigaki T, Wood CD, Darszon A, Tatsu Y, Yumoto N, Baba SA., Zoolog Sci. March 1, 2005; 22 (3): 293-9.

A sea urchin egg jelly peptide induces a cGMP-mediated decrease in sperm intracellular Ca(2+) before its increase., Nishigaki T, Wood CD, Tatsu Y, Yumoto N, Furuta T, Elias D, Shiba K, Baba SA, Darszon A., Dev Biol. August 15, 2004; 272 (2): 376-88.

Ion channel activity of membrane vesicles released from sea urchin sperm during the acrosome reaction., Schulz JR, De la Vega-Beltrán JL, Beltrán C, Vacquier VD, Darszon A., Biochem Biophys Res Commun. August 13, 2004; 321 (1): 88-93.

Measuring ion fluxes in sperm., Darszon A, Wood CD, Beltrán C, Sánchez D, Rodríguez E, Gorelik J, Korchev YE, Nishigaki T., Methods Cell Biol. January 1, 2004; 74 545-76.

Speract induces calcium oscillations in the sperm tail., Wood CD, Darszon A, Whitaker M., J Cell Biol. April 14, 2003; 161 (1): 89-101.                    

Intracellular sodium changes during the speract response and the acrosome reaction in sea urchin sperm., Rodríguez E, Darszon A., J Physiol. January 1, 2003; 546 (Pt 1): 89-100.

Ion channels in small cells and subcellular structures can be studied with a smart patch-clamp system., Gorelik J, Gu Y, Spohr HA, Shevchuk AI, Lab MJ, Harding SE, Edwards CR, Whitaker M, Moss GW, Benton DC, Sánchez D, Darszon A, Vodyanoy I, Klenerman D, Korchev YE., Biophys J. December 1, 2002; 83 (6): 3296-303.

A caged sperm-activating peptide that has a photocleavable protecting group on the backbone amide., Tatsu Y, Nishigaki T, Darszon A, Yumoto N., FEBS Lett. August 14, 2002; 525 (1-3): 20-4.

Sea urchin sperm cation-selective channels directly modulated by cAMP., Sánchez D, Labarca P, Darszon A., FEBS Lett. August 10, 2001; 503 (1): 111-5.

A sustained increase in intracellular Ca(2+) is required for the acrosome reaction in sea urchin sperm., González-Martínez MT, Galindo BE, de De La Torre L, Zapata O, Rodríguez E, Florman HM, Darszon A., Dev Biol. August 1, 2001; 236 (1): 220-9.

Time-resolved sperm responses to an egg peptide measured by stopped-flow fluorometry., Nishigaki T, Zamudio FZ, Possani LD, Darszon A., Biochem Biophys Res Commun. June 8, 2001; 284 (2): 531-5.

Real-time measurements of the interactions between fluorescent speract and its sperm receptor., Nishigaki T, Darszon A., Dev Biol. July 1, 2000; 223 (1): 17-26.

Participation of a K(+) channel modulated directly by cGMP in the speract-induced signaling cascade of strongylocentrotus purpuratus sea urchin sperm., Galindo BE, Beltrán C, Cragoe EJ, Darszon A., Dev Biol. May 15, 2000; 221 (2): 285-94.

Speract-receptor interaction and the modulation of ion transport in Strongylocentrotus purpuratus sea urchin sperm., Galindo BE, Nishigaki T, Rodríguez E, Sánchez D, Beltrán C, Darszon A., Zygote. January 1, 2000; 8 Suppl 1 S20-1.

Detection and functional characterization of ryanodine receptors from sea urchin eggs., Lokuta AJ, Darszon A, Beltrán C, Valdivia HH., J Physiol. July 1, 1998; 510 ( Pt 1) 155-64.

Acrosome reaction inactivation in sea urchin sperm., Guerrero A, García L, Zapata O, Rodríguez E, Darszon A., Biochim Biophys Acta. March 5, 1998; 1401 (3): 329-38.

Inositol triphosphate receptors in sea urchin sperm., Zapata O, Ralston J, Beltrán C, Parys JB, Chen JL, Longo FJ, Darszon A., Zygote. November 1, 1997; 5 (4): 355-64.

Membrane potential regulates sea urchin sperm adenylylcyclase., Beltrán C, Zapata O, Darszon A., Biochemistry. June 11, 1996; 35 (23): 7591-8.

A cAMP regulated K+-selective channel from the sea urchin sperm plasma membrane., Labarca P, Santi C, Zapata O, Morales E, Beltr'an C, Li'evano A, Darszon A., Dev Biol. March 15, 1996; 174 (2): 271-80.

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