Sulfated Triterpene Glycosides from the Far Eastern Sea Cucumber Cucumaria djakonovi: Djakonoviosides C1, D1, E1, and F1; Cytotoxicity against Human Breast Cancer Cell Lines; Quantitative Structure-Activity Relationships. Silchenko AS , Kalinovsky AI, Avilov SA, Popov RS, Chingizova EA, Menchinskaya ES, Zelepuga EA, Panina EG, Stepanov VG, Kalinin VI, Dmitrenok PS., Mar Drugs. November 22, 2023; 21 (12):
Djakonoviosides A, A1, A2, B1-B4 - Triterpene Monosulfated Tetra- and Pentaosides from the Sea Cucumber Cucumaria djakonovi: The First Finding of a Hemiketal Fragment in the Aglycones; Activity against Human Breast Cancer Cell Lines. Silchenko AS , Kalinovsky AI, Avilov SA, Popov RS, Dmitrenok PS, Chingizova EA, Menchinskaya ES, Panina EG, Stepanov VG, Kalinin VI, Stonik VA., Int J Mol Sci. July 5, 2023; 24 (13):
A Mass Spectrometry Database for Sea Cucumber Triterpene Glycosides. Silchenko AS , Avilov SA, Kalinin VI, Malyarenko TV , Stonik VA, Dmitrenok PS., Metabolites. June 23, 2023; 13 (7):
Chilensosides E, F, and G-New Tetrasulfated Triterpene Glycosides from the Sea Cucumber Paracaudina chilensis (Caudinidae, Molpadida): Structures, Activity, and Biogenesis. Silchenko AS , Avilov SA, Popov RS, Dmitrenok PS, Chingizova EA, Grebnev BB, Rasin AB, Kalinin VI., Mar Drugs. February 5, 2023; 21 (2):
The Isolation, Structure Elucidation and Bioactivity Study of Chilensosides A, A1, B, C, and D, Holostane Triterpene Di-, Tri- and Tetrasulfated Pentaosides from the Sea Cucumber Paracaudina chilensis (Caudinidae, Molpadida). Silchenko AS , Avilov SA, Andrijaschenko PV, Popov RS, Chingizova EA, Grebnev BB, Rasin AB, Kalinin VI., Molecules. November 7, 2022; 27 (21):
Structures and Biologic Activity of Chitonoidosides I, J, K, K1 and L-Triterpene Di-, Tri- and Tetrasulfated Hexaosides from the Sea Cucumber Psolus chitonoides. Silchenko AS , Avilov SA, Andrijaschenko PV, Popov RS, Chingizova EA, Dmitrenok PS, Kalinovsky AI, Rasin AB, Kalinin VI., Mar Drugs. May 30, 2022; 20 (6):
Triterpene Glycosides from the Far Eastern Sea Cucumber Psolus chitonoides: Chemical Structures and Cytotoxicities of Chitonoidosides E1, F, G, and H. Silchenko AS , Kalinovsky AI, Avilov SA, Andrijaschenko PV, Popov RS, Chingizova EA, Kalinin VI, Dmitrenok PS., Mar Drugs. December 7, 2021; 19 (12):
Structure-Activity Relationships of Holothuroid's Triterpene Glycosides and Some In Silico Insights Obtained by Molecular Dynamics Study on the Mechanisms of Their Membranolytic Action. Silchenko AS , Avilov SA, Kalinin VI., Mar Drugs. October 25, 2021; 19 (11):
Fucoidan from brown algae Fucus evanescens potentiates the anti-proliferative efficacy of asterosaponins from starfish Asteropsis carinifera in 2D and 3D models of melanoma cells. Malyarenko TV , Usoltseva RV, Silchenko AS , Kicha AA, Ivanchina NV, Ermakova SP., Int J Biol Macromol. August 31, 2021; 185 31-39.
Unusual Structures and Cytotoxicities of Chitonoidosides A, A1, B, C, D, and E, Six Triterpene Glycosides from the Far Eastern Sea Cucumber Psolus chitonoides. Silchenko AS , Kalinovsky AI, Avilov SA, Andrijaschenko PV, Popov RS, Dmitrenok PS, Chingizova EA, Kalinin VI., Mar Drugs. August 5, 2021; 19 (8):
Triterpene Glycosides from the Far Eastern Sea Cucumber Thyonidium (=Duasmodactyla) kurilensis (Levin): The Structures, Cytotoxicities, and Biogenesis of Kurilosides A3, D1, G, H, I, I1, J, K, and K1. Silchenko AS , Kalinovsky AI, Avilov SA, Andrijaschenko PV, Popov RS, Dmitrenok PS, Chingizova EA, Kalinin VI., Mar Drugs. March 27, 2021; 19 (4):
Kurilosides A1, A2, C1, D, E and F-Triterpene Glycosides from the Far Eastern Sea Cucumber Thyonidium (= Duasmodactyla) kurilensis (Levin): Structures with Unusual Non-Holostane Aglycones and Cytotoxicities. Silchenko AS , Kalinovsky AI, Avilov SA, Andrijaschenko PV, Popov RS, Dmitrenok PS, Chingizova EA, Kalinin VI., Mar Drugs. November 6, 2020; 18 (11):
Fucosylated Chondroitin Sulfates from the Sea Cucumbers Paracaudina chilensis and Holothuria hilla: Structures and Anticoagulant Activity. Silchenko AS , Grebnev BB, Stonik VA, Nifantiev NE, Usov AI., Mar Drugs. October 28, 2020; 18 (11):
Structures and Bioactivities of Quadrangularisosides A, A1, B, B1, B2, C, C1, D, D1-D4, and E from the Sea Cucumber Colochirus quadrangularis: The First Discovery of the Glycosides, Sulfated by C-4 of the Terminal 3-O-Methylglucose Residue. Synergetic Effect on Colony Formation of Tumor HT-29 Cells of these Glycosides with Radioactive Irradiation. Silchenko AS , Kalinovsky AI, Avilov SA, Andrijaschenko PV, Popov RS, Dmitrenok PS, Chingizova EA, Ermakova SP, Malyarenko OS, Dautov SS, Kalinin VI., Mar Drugs. July 28, 2020; 18 (8):
Structures and Bioactivities of Psolusosides B1, B2, J, K, L, M, N, O, P, and Q from the Sea Cucumber Psolus fabricii. The First Finding of Tetrasulfated Marine Low Molecular Weight Metabolites. Silchenko AS , Kalinovsky AI, Avilov SA, Kalinin VI, Andrijaschenko PV, Dmitrenok PS, Popov RS, Chingizova EA., Mar Drugs. November 6, 2019; 17 (11):
Modulation of Doxorubicin Intracellular Accumulation and Anticancer Activity by Triterpene Glycoside Cucumarioside A2-2. Silchenko A , Avilov S, Aminin D., Mar Drugs. October 23, 2019; 17 (11):
Non-holostane aglycones of sea cucumber triterpene glycosides. Structure, biosynthesis, evolution. Silchenko AS , Avilov SA, Stonik VA., Steroids. July 1, 2019; 147 42-51.
Structures and Bioactivities of Six New Triterpene Glycosides, Psolusosides E, F, G, H, H1, and I and the Corrected Structure of Psolusoside B from the Sea Cucumber Psolus fabricii. Silchenko AS , Kalinovsky AI, Avilov SA, Kalinin VI, Andrijaschenko PV, Dmitrenok PS, Popov RS, Chingizova EA, Ermakova SP, Malyarenko OS., Mar Drugs. June 14, 2019; 17 (6):
Cladolosides C4, D1, D2, M, M1, M2, N and Q, new triterpene glycosides with diverse carbohydrate chains from sea cucumber Cladolabes schmeltzii. An uncommon 20,21,22,23,24,25,26,27-okta-nor-lanostane aglycone. The synergism of inhibitory action of non-toxic dose of the glycosides and radioactive irradiation on colony formation of HT-29 cancer cells. Silchenko AS , Kalinovsky AI, Avilov SA, Andryjaschenko PV, Dmitrenok PS, Yurchenko EA, Ermakova SP, Malyarenko OS, Dolmatov IY , Kalinin VI., Carbohydr Res. October 1, 2018; 468 36-44.
Cladolosides O, P, P1-P3 and R, triterpene glycosides with two novel types of carbohydrate chains from the sea cucumberCladolabes schmeltzii. Inhibition of cancer cells colony formation and its synergy with radioactive irradiation. Silchenko AS , Kalinovsky AI, Avilov SA, Andryjaschenko PV, Dmitrenok PS, Yurchenko EA, Ermakova SP, Malyarenko OS, Dolmatov IY , Kalinin VI., Carbohydr Res. October 1, 2018; 468 73-79.
Holotoxin A₁ Induces Apoptosis by Activating Silchenko AS , Stonik VA, Park JI., Mar Drugs. April 10, 2018; 16 (4):
In vitro and in vivo anti-leukemic effects of cladoloside C2 are mediated by activation of Fas/ceramide synthase 6/p38 kinase/c- Silchenko AS , Stonik VA, Park JI., Oncotarget. December 8, 2017; 9 (1): 495-511.
Cucumarioside A₂-2 Causes Macrophage Activation in Mouse Spleen. Silchenko AS , Wang YM , Aminin DL., Mar Drugs. November 1, 2017; 15 (11):
Metabolite Profiling of Triterpene Glycosides of the Far Eastern Sea Cucumber Eupentacta fraudatrix and Their Distribution in Various Body Components Using LC-ESI QTOF-MS. Silchenko AS , Avilov SA, Kalinin VI, Dolmatov IY , Stonik VA, Dmitrenok PS., Mar Drugs. October 2, 2017; 15 (10):
Nine New Triterpene Glycosides, Magnumosides A₁-A₄, B₁, B₂, C₁, C₂ and C₄, from the Vietnamese Sea Cucumber Neothyonidium (=Massinium) magnum: Structures and Activities against Tumor Cells Independently and in Synergy with Radioactive Irradiation. Silchenko AS , Kalinovsky AI, Avilov SA, Kalinin VI, Andrijaschenko PV, Dmitrenok PS, Chingizova EA, Ermakova SP, Malyarenko OS, Dautova TN., Mar Drugs. August 16, 2017; 15 (8):
Cladolosides I1, I2, J1, K1, K2 and L1, monosulfated triterpene glycosides with new carbohydrate chains from the sea cucumber Cladolabes schmeltzii. Silchenko AS , Kalinovsky AI, Avilov SA, Andryjaschenko PV, Dmitrenok PS, Chingizova EA, Dolmatov IY , Kalinin VI., Carbohydr Res. June 5, 2017; 445 80-87.
The marine triterpene glycoside frondoside A induces p53-independent apoptosis and inhibits autophagy in urothelial carcinoma cells. Silchenko AS , Avilov SA, Honecker F, Stonik VA, Bokemeyer C, von Amsberg G., BMC Cancer. February 1, 2017; 17 (1): 93.
In vitro Anticancer Activities of Some Triterpene Glycosides from Holothurians of Cucumariidae, Stichopodidae, Psolidae, Holothuriidae and Synaptidae families. Silchenko AS , Bode AM, Dong Z, Stonik VA., Nat Prod Commun. September 1, 2016; 11 (9): 1239-1242.
Structures and Biogenesis of Fallaxosides D₄, D₅, D₆ and D₇, Trisulfated Non-Holostane Triterpene Glycosides from the Sea Cucumber Cucumaria fallax. Silchenko AS , Kalinovsky AI, Avilov SA, Andryjaschenko PV, Dmitrenok PS, Kalinin VI, Chingizova EA, Minin KV, Stonik VA., Molecules. July 20, 2016; 21 (7):
Colochiroside E, an Unusual Non-holostane Triterpene Sulfated Trioside from the Sea Cucumber Colochirus robustus and Evidence of the Impossibility of a 7(8)-Double Bond Migration in Lanostane Derivatives having an 18(16)-Lactone. Silchenko AS , Kalinovsky AI, Avilov SA, Andryjaschenko PV, Dmitrenok PS, Yurchenko EA, Dolmatov IY , Dautov SSh, Stonik VA, Kalinin VI., Nat Prod Commun. June 1, 2016; 11 (6): 741-6.
Colochirosides A₁, A₂, A₃, and D, Four Novel Sulfated Triterpene Glycosides from the Sea Cucumber Colochirus robustus (Cucumariidae, Dendrochirotida). Silchenko AS , Kalinovsky AI, Avilov SA, Andryjaschenko PV, Dmitrenok PS, Kalinin VI, Yurchenko EA, Dolmatov IY ., Nat Prod Commun. March 1, 2016; 11 (3): 381-7.
Colochirosides B1, B2, B3 and C, Novel Sulfated Triterpene Glycosides from the Sea Cucumber Colochirus robustus (Cucumariidae, Dendrochirotida). Silchenko AS , Kalinovsky AI, Avilov SA, Andryjaschenko PV, Dmitrenok PS, Kalinin VI, Yurchenko EA, Dolmatov IY ., Nat Prod Commun. October 1, 2015; 10 (10): 1687-94.
Structures and biological activities of cladolosides C3, E1, E2, F1, F2, G, H1 and H2, eight triterpene glycosides from the sea cucumber Cladolabes schmeltzii with one known and four new carbohydrate chains. Silchenko AS , Kalinovsky AI, Avilov SA, Andryjaschenko PV, Dmitrenok PS, Yurchenko EA, Dolmatov IY , Kalinin VI., Carbohydr Res. September 23, 2015; 414 22-31.
The Assignment of the Absolute Configuration of C-22 Chiral Center in the Aglycones of Triterpene Glycosides from the Sea Cucumber Cladolabes schmeltzi and Chemical Transformations of Cladoloside C. Silchenko AS , Avilov SA, Kalinin VI., Nat Prod Commun. July 1, 2015; 10 (7): 1167-70.
Cucumarioside E from the Far Eastern Sea Cucumber Cucumaria japonica (Cucumariidae, Dendrochirotida), New Minor Monosulfated Holostane Triterpene Pentaoside with Glucose as the Second Monosaccharide Residue. Silchenko AS , Kalinovsky AI, Dmitrenok PS, Kalinin VI, Mazeika AN, Vorobieva NS, Sanina NM, Kostetsky EY., Nat Prod Commun. June 1, 2015; 10 (6): 877-80.
Anticancer activity of sea cucumber triterpene glycosides. Silchenko AS , Avilov SA, Kalinin VI., Mar Drugs. March 6, 2015; 13 (3): 1202-23.
Triterpene glycosides of sea cucumbers (Holothuroidea, Echinodermata) as taxonomic markers. Silchenko AS , Stonik VA., Nat Prod Commun. January 1, 2015; 10 (1): 21-6.
Triterpene glycosides from the sea cucumber Cladolabes schmeltzii. II. Structure and biological action of cladolosides A1-A6 . Silchenko AS , Kalinovsky AI, Avilov SA, Andryjaschenko PV, Dmitrenok PS, Yurchenko EA, Dolmatov IY , Savchenko AM, Kalinin VI., Nat Prod Commun. October 1, 2014; 9 (10): 1421-8.
Kolgaosides A and B, two new triterpene glycosides from the Arctic deep water sea cucumber Kolga hyalina (Elasipodida: Elpidiidae). Silchenko AS , Kalinovsky AI, Avilov SA, Andryjashchenko PV, Fedorov SN, Dmitrenok PS, Yurchenko EA, Kalinin VI, Rogacheva AV, Gebruk AV., Nat Prod Commun. September 1, 2014; 9 (9): 1259-64.
Immunomodulatory action of triterpene glycosides isolated from the sea cucumber Actinocucumis typica. Structure-activity relationships. Silchenko AS , Avilov SA, Andryjashchenko PV, Kalinin VI, Padmakumar K., Nat Prod Commun. June 1, 2014; 9 (6): 771-2.
Structures of violaceusosides C, D, E and G, sulfated triterpene glycosides from the sea cucumber Pseudocolochirus violaceus (Cucumariidae, Dendrochirotida). Silchenko AS , Kalinovsky AI, Avilov SA, Andryjaschenko PV, Dmitrenok PS, Kalinin VI, Yurchenko EA, Dautov SS., Nat Prod Commun. March 1, 2014; 9 (3): 391-9.
Structure and biological action of cladolosides B1, B2, C, C1, C2 and D, six new triterpene glycosides from the sea cucumber Cladolabes schmeltzii. Silchenko AS , Kalinovsky AI, Avilov SA, Andryjaschenko PV, Dmitrenok PS, Yurchenko EA, Dolmatov IY , Kalinin VI, Stonik VA., Nat Prod Commun. November 1, 2013; 8 (11): 1527-34.
Inhibition of tumor cells multidrug resistance by cucumarioside A2-2, frondoside A and their complexes with cholesterol. Silchenko AS , Andryjashchenko PV, Kalinin VI, Stonik VA., Nat Prod Commun. October 1, 2013; 8 (10): 1377-80.
Triterpene glycosides from the sea cucumber Eupentacta fraudatrix. Structure and biological action of cucumariosides I1, I3, I4, three new minor disulfated pentaosides. Silchenko AS , Kalinovsky AI, Avilov SA, Andryjaschenko PV, Dmitrenok PS, Martyyas EA, Kalinin VI., Nat Prod Commun. August 1, 2013; 8 (8): 1053-8.
Structures and biological activities of typicosides A1, A2, B1, C1 and C2, triterpene glycosides from the sea cucumber Actinocucumis typica. Silchenko AS , Kalinovsky AI, Avilov SA, Andryjaschenko PV, Dmitrenok PS, Martyyas EA, Kalinin VI, Jayasandhya P, Rajan GC, Padmakumar KP., Nat Prod Commun. March 1, 2013; 8 (3): 301-10.
Structure of cucumarioside I2 from the sea cucumber Eupentacta fraudatrix (Djakonov et Baranova) and cytotoxic and immunostimulatory activities of this saponin and relative compounds. Silchenko AS , Kalinovsky AI, Avilov SA, Andryjaschenko PV, Dmitrenok PS, Menchinskaya ES, Aminin DL, Kalinin VI., Nat Prod Res. January 1, 2013; 27 (19): 1776-83.
Antitumor activity of cucumarioside A2-2. Silchenko AS , Avilov SA, Kalinin VI, Aminin DL., Chemotherapy. January 1, 2013; 59 (3): 181-91.
Triterpene glycosides from the sea cucumber Eupentacta fraudatrix. Structure and biological activity of cucumariosides B1 and B2, two new minor non-sulfated unprecedented triosides. Silchenko AS , Kalinovsky AI, Avilov SA, Andryjaschenko PV, Dmitrenok PS, Martyyas EA, Kalinin VI., Nat Prod Commun. September 1, 2012; 7 (9): 1157-62.
Triterpene glycosides from the sea cucumber Eupentacta fraudatrix. Structure and cytotoxic action of cucumariosides A2, A7, A9, A10, an, A13 and A14, seven new minor non-sulfated tetraosides and an aglycone with an uncommon 18-hydroxy group. Silchenko AS , Kalinovsky AI, Avilov SA, Andryjaschenko PV, Dmitrenok PS, Martyyas EA, Kalinin VI., Nat Prod Commun. July 1, 2012; 7 (7): 845-52.
Triterpene glycosides from the sea cucumber Eupentacta fraudatrix. Structure and biological action of cucumariosides A1, A3, A4, A5, A6, A12 and A15, seven new minor non-sulfated tetraosides and unprecedented 25-keto, 27-norholostane aglycone. Silchenko AS , Kalinovsky AI, Avilov SA, Andryjaschenko PV, Dmitrenok PS, Martyyas EA, Kalinin VI., Nat Prod Commun. April 1, 2012; 7 (4): 517-25.
