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ECB-MORPHOLINO-26398322

Morpholino Name: nlk MO2
Synonyms: NLK 5'UTR
Target mRNA: nlk
Derived from:

Morpholino Type: translation blocking morpholino (5' UTR)
Sequence: 5' TCGGAGGCAGACCAGCAGCGAGAAA 3'

Source: Gene Tools LLC


Target mRNA S. purpuratus L. variegatus
Identities 23/25 23/25
genome
MO
5' TTTCTCGCTGCTCGTCTCCCTCCGA 3'
   |||||||||||| |||| |||||||
3' AAAGAGCGACGACCAGACGGAGGCT 5'
5' TTTCTCGCTGCTGGTCTCCCCCCGA 3'
   ||||||||||||||||| || ||||
3' AAAGAGCGACGACCAGACGGAGGCT 5'
    
Genomic Alignments Position Identity Strand Target Target mRNA
S. purpuratus 5.0 NW_022145605.1:7864802..7864826 23/25 Antisense target nlk
NW_022145610.1:29318291..29318315 21/25 Sense off-target LOC105446374
L. variegatus 3.0 chr2:77351102..77351126 23/25 Antisense target nlk
chr3:4559089..4559113 21/25 Sense unknown
Publications
???morpholino.displaySummary.papersFirst??? Nemo-like kinase (NLK) acts downstream of Notch/Delta signalling to downregulate TCF during mesoderm induction in the sea urchin embryo., Development 2006  
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