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Echinobase

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ECB-ANTIBODY-26396164

Antibody Name: myp Ab1

Common Name: major yolk protein

RRID:
Synonyms: major yolk platelet glycoprotein

Antigens
Gene: myp

Clone Type: Polyclonal
Source:

Antibody
Clone Number
Purification Affinity Purification
Isotype IgG
Host Organism rabbit
Echinoderm Reactivity S. purpuratus, L. pictus
Non-Echinoderm Reactivity
Description: Reacts with the intact and proteolytic products of a ~160 kDa yolk platelet glycoprotein that is conserved among echinoids (Arbacia punctulata, Dendraster excentricus, Heliocidaris tuberculata) up to the pluteus larval stage. Created by the Lennarz lab formerly within the M. D. Anderson Cancer Center at the University of Texas.
Immunogen
Name 90-kDa glycoprotein
Type polypeptide
Post Translational Modifications Proteolysis
Source Organism purple sea urchin
Description Abundant protein product excised from polyacrylamide gel utilized to separate gastrula stage polymannose glycoproteins.
Sequence
Reported Usage
enzyme-linked immunosorbent assay
immunohistochemistry
western blot
Publications
First: Structure of a major yolk glycoprotein and its processing pathway by limited proteolysis are conserved in echinoids., Dev Biol 1989  
Most recent: The "lecithotrophic" sea urchin Heliocidaris erythrogramma lacks typical yolk platelets and yolk glycoproteins., Dev Biol 1990  
View All Papers