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Echinobase

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ECB-ANTIBODY-26396030

Antibody Name: tubb1 Ab5

Common Name: tubulin beta 1 class 6

RRID:
Synonyms: C9, beta-tubulin

Antigens
Gene: tubb1

Clone Type: Monoclonal
Source:

Antibody
Clone Number C9
Purification
Isotype IgM
Host Organism mouse
Echinoderm Reactivity S. purpuratus, L. pictus
Non-Echinoderm Reactivity human
Description: Monospecific antibody that recognizes a ~50 kDa protein in sea urchin sperm axonemes that has been demonstrated to inhibit sperm motility. Created and screened from a panel of monoclonal antibodies at laboratory of Claude Gagnon at the Urology Research Laboratory, within the Royal Victoria Hospital at McGill University in Montreal, Canada. Also reacts with Arbacia lixula and dinoflagellates (Oxyrhhis marina).
Immunogen
Name Whole Sperm Axonemes
Type polypeptide
Post Translational Modifications None
Source Organism Lytechinus pictus
Description Several proteins purified from sea urchin spermatozoa.
Sequence
Reported Usage
enzyme-linked immunosorbent assay
immunofluorescence
western blot
Publications
???displayAntibody.papersFirst??? Inhibition of flagellar beat frequency by a new anti-beta-tubulin antibody., Cell Motil Cytoskeleton 1996  
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