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Echinobase

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ECB-ANTIBODY-26395367

Antibody Name: dnai1 Ab1

Common Name: dynein axonemal intermediate chain 1

RRID:
Synonyms: D1, DYI2, ODA-IC1, dynein intermediate chain IC1

Antigens
Gene: dnai1

Clone Type: Monoclonal
Source:

Antibody
Clone Number D1
Purification
Isotype IgM
Host Organism mouse
Echinoderm Reactivity S. purpuratus, P. lividus, L. pictus
Non-Echinoderm Reactivity human
Description: Antibody selected from a screen of monoclonal antibodies due to its ability to inhibit sperm motility by targeting a 142-kDa axonemal protein in the outer arm. Created in the Gagnon lab at the Urology Research Laboratory in Royal Victoria Hospital at McGill University in Montreal, Canada. Also reacts with Arbacia lixula and Oxyrrhis marina.
Immunogen
Name Sperm Axonemes
Type other immunogen type
Post Translational Modifications None
Source Organism Lytechinus pictus
Description Resuspended axoneme pellet purified from spermatozoa.
Sequence
Reported Usage
immunofluorescence
western blot
Publications
???displayAntibody.papersFirst??? A monoclonal antibody against the dynein IC1 peptide of sea urchin spermatozoa inhibits the motility of sea urchin, dinoflagellate, and human flagellar axonemes., Mol Biol Cell 1994  
???displayAntibody.papersRecent??? Differential distribution of glutamylated tubulin isoforms along the sea urchin sperm axoneme., Mol Reprod Dev 2002  
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